Targeting cytotoxic T lymphocytes for cancer immunotherapy

被引：80
|
作者：
Maher, J
Davies, ET
机构：
[1] Guys Hosp, Guys Kings & St Thomass Sch Med, Div Canc Studies, Canc Res UK Breast Canc Biol Grp, London SE1 9RT, England
[2] Kings Coll Hosp London, Rayne Inst, Dept Clin Immunol, London SE5 9NU, England
来源：
BRITISH JOURNAL OF CANCER | 2004年 / 91卷 / 05期
关键词：
CTL; vaccine; adoptive immunotherapy; gene therapy;
D O I：
10.1038/sj.bjc.6602022
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In light of their preeminent role in cellular immunity, there is considerable interest in targeting of cytotoxic T-lymphocytes to cancer. This review summarises the active and passive immunotherapeutic approaches under development to achieve this goal, emphasising how recent advances in tumour immunology and gene transfer have impacted upon this field.
引用
收藏
页码：817 / 821
页数：5
相关论文
共 50 条
  • [41] Reinforcement of Cancer Immunotherapy by Adoptive Transfer of Cblb-Deficient Cytotoxic T Lymphocytes Combined with a Dendritic Cell Vaccine
    Lutz-Nicoladoni, Christina
    Stoizner, Patrizia
    Piroher, Magdalena
    Wallner, Stephanie
    Wolf, Anna Maria
    Gastl, Guenther
    Penninger, Josef
    Baier, Gottfried
    Wolf, Dominik
    BLOOD, 2010, 116 (21) : 421 - 422
  • [42] 'Off-the-shelf' immunotherapy with iPSC-derived rejuvenated cytotoxic T lymphocytes
    Ando, Miki
    Nakauchi, Hiromitsu
    EXPERIMENTAL HEMATOLOGY, 2017, 47 : 2 - 12
  • [43] Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models
    Li, Anning
    Wu, Yue
    Linnoila, Jenny
    Pulli, Benjamin
    Wang, Cuihua
    Zeller, Matthias
    Ali, Muhammad
    Lewandrowski, Grant K.
    Li, Jinghui
    Tricot, Benoit
    Keliher, Edmund
    Wojtkiewicz, Gregory R.
    Fulci, Giulia
    Feng, Xiaoyuan
    Tannous, Bakhos A.
    Yao, Zhenwei
    Chen, John W.
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2016, 65 (12) : 1545 - 1554
  • [44] Analysis of cytotoxic activity of the CD4(+) T lymphocytes generated by local immunotherapy
    Katsumoto, Y
    Monden, T
    Takeda, T
    Haba, A
    Ito, Y
    Wakasugi, E
    Wakasugi, E
    Wakasugi, T
    Sekimoto, M
    Kobayashi, T
    Shiozaki, H
    Shimano, T
    Monden, M
    BRITISH JOURNAL OF CANCER, 1996, 73 (01) : 110 - 116
  • [45] Vaccines targeting helper T cells for cancer immunotherapy
    Meissen, Marit
    Slingluff, Craig L., Jr.
    CURRENT OPINION IN IMMUNOLOGY, 2017, 47 : 85 - 92
  • [46] Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy
    Le Bourgeois, Thibault
    Strauss, Laura
    Aksoylar, Halil-Ibrahim
    Daneshmandi, Saeed
    Seth, Pankaj
    Patsoukis, Nikolaos
    Boussiotis, Vassiliki A.
    FRONTIERS IN ONCOLOGY, 2018, 8
  • [47] Targeting the epigenome to reinvigorate T cells for cancer immunotherapy
    Dian Xiong
    Lu Zhang
    Zhi-Jun Sun
    Military Medical Research, 10
  • [48] Targeting the epigenome to reinvigorate T cells for cancer immunotherapy
    Dian Xiong
    Lu Zhang
    ZhiJun Sun
    Military Medical Research, 2024, 11 (06) : 863 - 886
  • [49] Targeting Resident Memory T Cells for Cancer Immunotherapy
    Blanc, Charlotte
    Hans, Sophie
    Thi Tran
    Granier, Clemence
    Saldman, Antonin
    Anson, Marie
    Oudard, Stephane
    Tartour, Eric
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [50] Targeting adenosine and regulatory T cells in cancer immunotherapy
    Churov, Alexey
    Zhulai, Galina
    HUMAN IMMUNOLOGY, 2021, 82 (04) : 270 - 278
12345