The Management of Young Children With a Likely Infectious Condition Presenting Moderate to Severe Neutropenia

被引：1
|
作者：
Larouche, Valerie [1 ]
Pelland-Marcotte, Marie-Claude [1 ]
Blanchet, Marie-Eve [1 ]
Simonyan, David [2 ]
Belanger, Richard E. [1 ,3 ]
机构：
[1] Univ Laval, CHU Quebec, Res Ctr, Dept Pediat, Quebec City, PQ, Canada
[2] Univ Laval, CHU Quebec, Res Ctr, Clin & Evaluat Res Platform, Quebec City, PQ, Canada
[3] CHU Quebec, Res Ctr, Populat Hlth & Optimal Hlth Practices Res Branch, Quebec City, PQ, Canada
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2020年 / 42卷 / 08期
关键词：
children; neutropenia; leucopenia; infectious disease; TRANSIENT NEUTROPENIA; FEBRILE NEUTROPENIA; ETIOLOGIES;
D O I：
10.1097/MPH.0000000000001749
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Objective: The objective of this study was to describe the outcome of healthy children presenting with newly-diagnosed neutropenia in an infectious context. Results: A total of 184 episodes of neutropenia were included in children 3 months to 5 years of age. There were 118 (64%) episodes of moderate neutropenia and 66 (36%) of severe neutropenia (SN). SN episodes were more likely related to intensification of antibiotic regimen used and further investigations. The median duration of neutropenia was 8.5 days. Chronic benign neutropenia occurred in 7 (4%) patients. Conclusion: SN led to intensification of antibiotic therapy, but no children encountered an unfavorable outcome and the neutropenia episodes were short-lived.
引用
收藏
页码：E778 / E782
页数：5
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