The Management of Young Children With a Likely Infectious Condition Presenting Moderate to Severe Neutropenia

被引：1
|
作者：
Larouche, Valerie [1 ]
Pelland-Marcotte, Marie-Claude [1 ]
Blanchet, Marie-Eve [1 ]
Simonyan, David [2 ]
Belanger, Richard E. [1 ,3 ]
机构：
[1] Univ Laval, CHU Quebec, Res Ctr, Dept Pediat, Quebec City, PQ, Canada
[2] Univ Laval, CHU Quebec, Res Ctr, Clin & Evaluat Res Platform, Quebec City, PQ, Canada
[3] CHU Quebec, Res Ctr, Populat Hlth & Optimal Hlth Practices Res Branch, Quebec City, PQ, Canada
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2020年 / 42卷 / 08期
关键词：
children; neutropenia; leucopenia; infectious disease; TRANSIENT NEUTROPENIA; FEBRILE NEUTROPENIA; ETIOLOGIES;
D O I：
10.1097/MPH.0000000000001749
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Objective: The objective of this study was to describe the outcome of healthy children presenting with newly-diagnosed neutropenia in an infectious context. Results: A total of 184 episodes of neutropenia were included in children 3 months to 5 years of age. There were 118 (64%) episodes of moderate neutropenia and 66 (36%) of severe neutropenia (SN). SN episodes were more likely related to intensification of antibiotic regimen used and further investigations. The median duration of neutropenia was 8.5 days. Chronic benign neutropenia occurred in 7 (4%) patients. Conclusion: SN led to intensification of antibiotic therapy, but no children encountered an unfavorable outcome and the neutropenia episodes were short-lived.
引用
收藏
页码：E778 / E782
页数：5
相关论文
共 50 条
  • [1] The Cost of a "Benign" Condition: Healthcare Utilization and Infectious Outcomes in Young Children with Autoimmune Neutropenia
    Kirk, Susan E.
    Grimes, Amanda Bell
    Shelke, Sayali
    Despotovic, Jenny M.
    Powers, Jacquelyn M.
    BLOOD, 2018, 132
  • [2] The cost of a "benign" condition: Healthcare utilization and infectious outcomes in young children with primary autoimmune neutropenia
    Kirk, Susan E.
    Grimes, Amanda Bell
    Shelke, Sayali
    Despotovic, Jenny M.
    Powers, Jacquelyn M.
    PEDIATRIC BLOOD & CANCER, 2020, 67 (04)
  • [3] Management of Severe and Moderate Hypercholesterolemia in Young Adults
    Newton, Shauna L.
    Hoffmann, Alexander P.
    Haidermota, Sara
    Natarajan, Pradeep
    Honigberg, Michael C.
    CIRCULATION, 2021, 144
  • [4] Xanthogranulomatous Osteomyelitis Presenting as a Subacute Infectious Condition in the Fibula of a Young Female
    Ju, Seong Gyeong
    Yoon, Yu Sung
    Cha, Jang Gyu
    Chin, Susie
    INVESTIGATIVE MAGNETIC RESONANCE IMAGING, 2023, 27 (03) : 163 - 166
  • [5] Management of Severe and Moderate Hypercholesterolemia in Young Women and Men
    Newton, Shauna L.
    Hoffmann, Alexander P.
    Yu, Zhi
    Haidermota, Sara
    Natarajan, Pradeep
    Honigberg, Michael C.
    JAMA CARDIOLOGY, 2022, 7 (02) : 227 - 230
  • [6] LOW RISK OF BACTEREMIA IN OTHERWISE HEALTHY CHILDREN PRESENTING WITH FEVER AND SEVERE NEUTROPENIA
    Perez-Mendez, Carlos
    Molinos-Norniella, Cristina
    Moran-Poladura, Maria
    Fernandez-Rodriguez, Eloy
    Suarez-Castanon, Cristina
    Solis-Sanchez, Gonzalo
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2010, 29 (07) : 671 - 672
  • [7] INFECTIOUS COMPLICATIONS IN CHILDREN WITH SEVERE CONGENITAL, AUTOIMMUNE OR IDIOPATHIC NEUTROPENIA: A RETROSPECTIVE STUDY FROM THE ITALIAN NEUTROPENIA REGISTRY
    Fioredda, Francesca
    Calvillo, Michaela
    Burlando, Oriana
    Riccardi, Francesca
    Caviglia, Ilaria
    Tucci, Fabio
    Bonanomi, Sonia
    Ghilardi, Roberta
    Martire, Baldassare
    Farruggia, Piero
    Mastrodicasa, Elena
    Barone, Angelica
    Castagnola, Elio
    Dufour, Carlo
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2013, 32 (04) : 410 - 412
  • [8] Individualizing literacy instruction for young children with moderate to severe disabilities
    Kliewer, C
    Landis, D
    EXCEPTIONAL CHILDREN, 1999, 66 (01) : 85 - 100
  • [9] An update on management of severe acute infectious gastroenteritis in children
    O'Ryan, Miguel
    Lucero, Yalda
    O'Ryan-Soriano, Miguel A.
    Ashkenazi, Shai
    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2010, 8 (06) : 671 - 682
  • [10] MANAGEMENT OF ACUTE INFECTIOUS DIARRHEA IN YOUNG-CHILDREN
    BOISSIERE, H
    SAINTJACQUES, I
    SEMAINE DES HOPITAUX THERAPEUTIQUE, 1977, 53 (04): : 227 - 230
12345