Tagraxofusp, an Anti-CD123 Therapy, in Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm: Sub-Analysis of a Pivotal Trial by Age and Baseline Disease Involvement

被引：0
|
作者：
Pemmaraju, Naveen [1 ]
Konopleva, Marina [1 ]
Sweet, Kendra [2 ]
Stein, Anthony [3 ]
Vasu, Sumithira [4 ]
Rizzieri, David [5 ]
Wang, Eunice S. [6 ]
Kantarjian, Hagop [1 ]
Brooks, Chris [7 ]
Mughal, Tariq [7 ]
Lane, Andrew [8 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[3] City Hope Natl Med Ctr, Duarte, CA USA
[4] Ohio State Univ, Columbus, OH USA
[5] Duke Univ, Med Ctr, Durham, NC USA
[6] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA
[7] Stemline Therapeut Inc, New York, NY USA
[8] Dana Farber Canc Inst, Boston, MA USA
来源：
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2022年 / 22卷
关键词：
AML; myeloid neoplasm; targeted therapy; CD123; tagraxofusp; BPDCN; Phase I/II;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
AML-465
引用
收藏
页码：S254 / S254
页数：1
相关论文
共 42 条
  • [21] Breakthrough in Blastic Plasmacytoid Dendritic Cell Neoplasm Cancer Therapy Owing to Precision Targeting of CD123
    Zanotta, Serena
    Galati, Domenico
    De Filippi, Rosaria
    Pinto, Antonio
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (03)
  • [22] Case Report of Anti-CD123 Chimeric Antigen Receptor T-Cell Therapy Followed by Radiotherapy for a Recurrence of Blastic Plasmacytoid Dendritic Cell Neoplasm After Allogeneic Hematopoietic Stem Cell Transplantation
    Jiang, Yi-li
    Li, Qing
    Yuan, Ting
    Jiang, Yan-yu
    Deng, Qi
    ONCOTARGETS AND THERAPY, 2020, 13 : 3425 - 3430
  • [23] Results of Pivotal Phase 2 Trial of SL-401 in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
    Pemmaraju, Naveen
    Sweet, Kendra L.
    Lane, Andrew A.
    Stein, Anthony S.
    Vasu, Sumithira
    Blum, William
    Rizzieri, David A.
    Wang, Eunice S.
    Duvic, Madeleine
    Aung, Phyu
    Shubert, Danielle
    Spence, Sharon
    Shemesh, Shay
    Chen, Janice
    Brooks, Christopher
    Bergstein, Ivan
    McDonald, Peter
    Goswami, Trishna
    Sloan, John Mark
    Lancet, Jeffrey E.
    Kantarjian, Hagop M.
    Konopleva, Marina
    BLOOD, 2017, 130
  • [24] Immunohistochemical analysis of CD123, CD56 and CD4 for the diagnosis of minimal bone marrow involvement by blastic plasmacytoid dendritic cell neoplasm
    Hwang, Keumrock
    Park, Chan-Jeoung
    Jang, Seongsoo
    Chi, Hyun-Sook
    Huh, Joo-Ryung
    Lee, Je Hwan
    Suh, Cheolwon
    Lee, Kyoo Hyung
    HISTOPATHOLOGY, 2013, 62 (05) : 764 - 770
  • [25] Optimization of the CD123 CAR T-cell scFv for the treatment of patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
    Fredon, M.
    Poussard, M.
    Biichle, S.
    Anna, F.
    Bonnefoy, F.
    Bole-Richard, E.
    Renosi, F.
    Caumartin, J.
    Loustau, M.
    Adotevi, O.
    Saas, P.
    Angelot-Delettre, F.
    Galaine, J.
    Garnache-Ottou, F.
    HUMAN GENE THERAPY, 2021, 32 (19-20) : A37 - A37
  • [26] Blastic Plasmacytoid Dendritic Cell Neoplasm Treated with Approved CD123-Targeted Therapy Tagraxofusp: The First European Real-World Evidence Prospective Registry of First-Line Adult Patients
    Platzbecker, Uwe
    Angelucci, Emanuele
    Montesinos, Pau
    Lemoli, Roberto Massimo
    Spyridonidis, Alexandros
    Mughal, Tariq, I
    Paley, Carole
    Riggi, Marcello
    Mohty, Mohamad
    BLOOD, 2022, 140 : 11710 - 11712
  • [27] Findings From an Observational, Multicenter, Retrospective Analysis of Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm Treated With Tagraxofusp in the European Expanded Access Program
    Herling, Marco
    Deconinck, Eric
    Anant, Madhu
    Manteigas, David
    Riggi, Marcello
    Mughal, Tariq
    Angelucci, Emanuele
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 : S338 - S338
  • [28] IMMUNOHISTOCHEMISTRY (CD123, CD56 AND CD4) REVEALS MINIMAL BONE MARROW INVOLVEMENT IN CASES OF BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
    Hwang, K.
    Park, C. J.
    Chi, H. S.
    Jang, S.
    Park, S. J.
    Huh, J. R.
    Lee, J. H.
    Suh, C.
    Lee, K. H.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 547 - 548
  • [29] First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases
    Weili Sun
    Huaying Liu
    Young Kim
    Nicole Karras
    Anna Pawlowska
    Debbie Toomey
    Wade Kyono
    Paul Gaynon
    Joseph Rosenthal
    Anthony Stein
    Journal of Hematology & Oncology, 11
  • [30] First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases
    Sun, Weili
    Liu, Huaying
    Kim, Young
    Karras, Nicole
    Pawlowska, Anna
    Toomey, Debbie
    Kyono, Wade
    Gaynon, Paul
    Rosenthal, Joseph
    Stein, Anthony
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018, 11
12345