Functional rafts in cell membranes

被引：8022
作者：
Simons, K [1 ]
Ikonen, E [1 ]
机构：
[1] NATL PUBL HLTH INST, DEPT BIOCHEM, SF-00300 HELSINKI, FINLAND
来源：
NATURE | 1997年 / 387卷 / 6633期
关键词：
D O I：
10.1038/42408
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A new aspect of cell membrane structure is presented, based on the dynamic clustering of sphingolipids and cholesterol to form rafts that move within the fluid bilayer. It is proposed that these rafts function as platforms for the attachment of proteins when membranes are moved around inside the cell and during signal transduction.
引用
收藏
页码：569 / 572
页数：4
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