Real-time monitoring of rolling circle amplification using aggregation-induced emission: applications in biological detection

被引：39
|
作者：
Jiang, Hong-Xin [1 ,2 ,3 ]
Zhao, Meng-Yao [1 ,2 ,3 ]
Niu, Chen-Di [1 ,2 ,3 ]
Kong, De-Ming [1 ,2 ,3 ]
机构：
[1] Nankai Univ, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China
[2] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China
[3] Nankai Univ, Tianjin Key Lab Biosensing & Mol Recognit, Res Ctr Analyt Sci, Tianjin 300071, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 92期
基金：
中国国家自然科学基金;
关键词：
FLUORESCENT-PROBE; DNA-LIGASE; MOLECULAR BEACONS; PROTEIN; QUANTIFICATION; APOPTOSIS; DNAZYME; ASSAY;
D O I：
10.1039/c5cc07340e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report that QATPE, an aggregation-induced emission-active tetraphenylethene dye, can be used as a non-sequence-specific ssDNA probe for real-time monitoring of all rolling circle amplification (RCA) reactions, thus making RCA more suitable for biosensing applications.
引用
收藏
页码：16518 / 16521
页数：4
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