Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT)

被引：218

作者：

Moss, Raymond L. ^{[1
]}

机构：

[1] European Commiss, Joint Res Ctr, Inst Energy & Transport, NL-1755 LE Petten, Netherlands

来源：

APPLIED RADIATION AND ISOTOPES | 2014年 / 88卷

关键词：

BNCT; Clinical trials; Boron compounds; Accelerators; GLIOBLASTOMA-MULTIFORME; CLINICAL-TRIAL; BRAIN-TUMORS; RECURRENT HEAD; NECK-CANCER; BEAM; FACILITY; EXPERIENCE; MELANOMA; SURVIVAL;

D O I：

10.1016/j.apradiso.2013.11.109

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The first BNCT trials took place in the USA in the early 1960's, yet BNCT is still far from mainstream medicine. Nonetheless, in recent years, reported results in the treatment of head and neck cancer and recurrent glioma, coupled with the progress in developing linear accelerators specifically for BNCT applications, have given some optimism to the future of BNCT. This article provides a brief reminder on the ups and downs of the history of BNCT and supports the view that controlled and prospective clinical trials with a modern design will make BNCT an evidence-based treatment modality within the coming decade. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：2 / 11

页数：10

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