cancer;
metastatic disease;
vertebral body metastasis;
D O I:
10.1097/01.SMJ.0000053923.35326.0D
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Cancer is the second leading cause of death in the United States, and vertebral body metastases often occur in systemic malignancy. Metastatic spinal tumors may present with pain or neurologic deficit, or may be detected during screening examinations in patients with known malignancy. Management of spinal metastases remains controversial. The role of surgery, especially decompressive laminectomy without stabilization, has been questioned. Recent series attest to the beneficial role of surgery, emphasizing anterior and combined decompression and stabilization procedures. We review the relevant literature on metastatic spinal tumors, assessing imaging strategies, adjuvant treatment, patient selection, and results and complications. Operative decompression and stabilization is an important tool in the management of spinal metastatic disease. Patient selection and appropriate use of anterior and/or posterior decompression and stabilization are necessary to optimize surgical results.
机构:
Fdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, ItalyFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Costa, Francesco
Restelli, Francesco
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机构:
Fdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, ItalyFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Restelli, Francesco
Innocenti, Niccolo
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机构:
Fdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, ItalyFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Innocenti, Niccolo
Zileli, Mehmet
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机构:
Sanko Univ, Fac Med, Dept Pathol, Gaziantep, TurkiyeFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Zileli, Mehmet
Vaishya, Sandeep
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机构:
Fortis Mem Hosp, New Delhi, IndiaFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Vaishya, Sandeep
Zygourakis, Corinna
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机构:
Stanford Univ, Sch Med, Palo Alto, CA USAFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Zygourakis, Corinna
Pojskic, Mirza
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机构:
Philipps Univ Marburg, Marburg, GermanyFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Pojskic, Mirza
Yaman, Onur
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机构:
Mem Bahcelievler Hosp, Istanbul, TurkiyeFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy
Yaman, Onur
Sharif, Salman
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机构:
Liaquat Natl Hosp & Med Coll, Karachi, PakistanFdn IRCCS Ist Neurol Carlo Besta, Dept Neurosurg, Spine Surg Unit NCH4, Via Celoria 11, I-20133 Milan, Italy