Pharmacovigilance, risks and adverse effects of self-medication

被引：46

作者：

Montastruc, Jean-Louis ^{[1
,2
]}

Bondon-Guitton, Emmanuelle ^{[1
]}

Abadie, Delphine ^{[1
]}

Lacroix, Isabelle ^{[1
]}

Berreni, Aurelia ^{[1
]}

Pugnet, Gregory ^{[3
]}

Durrieu, Genevieve ^{[1
]}

Sailler, Laurent ^{[3
]}

Giroud, Jean-Paul ^{[2
]}

Damase-Michel, Christine ^{[1
]}

Montastruc, Francois ^{[1
]}

机构：

[1] CHU Toulouse, Serv Pharmacol Med & Clin, Ctr Midi Pyrenees Pharmacovigilance Pharmacoepide, Pharmacopole Midi Pyrenees,Fac Med,CIC Inserm 143, 37 Allees Jules Guesde, F-31000 Toulouse, France

[2] Acad Natl Med, F-75000 Paris, France

[3] CHU Toulouse, Fac Med, Hop Purpan, Serv Med Interne, F-31000 Toulouse, France

来源：

THERAPIE | 2016年 / 71卷 / 02期

关键词：

Self-medication; Pharmacovigilance; Medical adverse effects; Risks; Painkillers; Non-steroid anti-inflammatory drugs; Benzodiazepines; OVER-THE-COUNTER; DRUG-REACTIONS; SIDE; MULTICENTER; PREVALENCE; DATABASE;

D O I：

10.1016/j.therap.2016.02.012

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Self-medication means resorting to one or more drugs in order to treat oneself without the help of a doctor. This phenomenon is developing fast. In this review, we will discuss the main definitions of self-medication; we will then present a few important characteristics of this therapeutic practice: prevalence, reasons, populations involved and drugs used. Whilst the theoretical risks of self-medication have been abundantly discussed in the literature (adverse effects, interactions, product, dosage or treatment duration errors, difficulty in self-diagnosis, risk of addiction or abuse...), there is in fact very little detailed pharmacovigilance data concerning the characteristics and the consequences of this usage in real life. This study therefore describes the all too rare data that is available: patients, clinical characteristics, "seriousness'' and drugs involved in the adverse effects of self-medication. It also discusses leads to be followed in order to minimize medication risks, which are obviously not well known and clearly not sufficiently notified. (C) 2016 Societe francaise de pharmacologie et de therapeutique. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：257 / 262

页数：6

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