Objective: The purpose of this study is to analyze the different clinical manifestations of neonatal sepsis, the related factors leading to neonatal complications, and the related factors of common complications, so as to provide a theoretical basis and logical proof for the treatment of neonatal sepsis. Methods: This article collects clinical data of 110 cases of septicaemic neonates, compare the clinical characteristics, general conditions, pathogen distribution, laboratory test data of two groups of patients with septicaemic, and conduct statistics and analysis. Results: The results showed that among 110 patients, there were 53 (48%) cases of premature septicaemic and 9 (8%) cases were infected during pregnancy. There were 7 (6%) cases of amniotic fluid contamination. There were 26(23%) cases of risk factors in the womb. 25 (23%) cases of children with multiple symptoms., The positive rates of white blood cell and platelet examination, c-reactive protein examination and neutrophil rod-nucleus/neutrophil examination were 59.64%, 38.77%, 38.6% and 5.66% respectively. Procalcitonin level was positively correlated with c-reactive protein (P<0.01, r=0.7). Among them, 6 (5.45%) cases were positive in blood culture, including 3 (2.72%) cases of staphylococcus epidermidis, 2(1.81%)cases of staphylococcus aureus and 1(0.90%)case of escherichia coli. Conclusion: The clinical manifestations of neonatal sepsis are relatively concealed, and antibiotics are used reasonably in the early treatment process to deal with the symptoms of the disease and promote the improvement of the treatment effect.
