Comparative genomics in vertebrate evolution and development

被引：2
|
作者：
Amemiya, Chris T.
Gomez-Chiarri, Marta
机构：
[1] Virginia Mason, Benaroya Res Inst, Mol Genet Program, Seattle, WA 98101 USA
[2] Univ Rhode Isl, Dept Fisheries Anim & Vet Sci, Kingston, RI 02881 USA
来源：
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY | 2006年 / 305A卷 / 09期
关键词：
D O I：
10.1002/jez.a.308
中图分类号：
Q95 [动物学];
学科分类号：
071002 ;
摘要：
The vast quantities of publicly available DNA sequencing data and genome resources are enabling biologists to investigate age-old problems in biology that were not addressable previously. In this review, we discuss how comparative genomics is practiced and how the data can be used to make biological inferences with respect to vertebrate evolution and development. Examples are taken from the well-known HOX clusters, which are always a high-priority target for genomic analyses due to their inferred role in the evolution of metazoans. In addition, we briefly discuss the application of genomic approaches to problems in comparative endocrinology.
引用
收藏
页码：672 / 682
页数：11
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