The kinship2 R Package for Pedigree Data

被引:134
|
作者
Sinnwell, Jason P. [1 ]
Therneau, Terry M. [1 ]
Schaid, Daniel J. [1 ]
机构
[1] Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Rochester, MN 55905 USA
基金
美国国家卫生研究院;
关键词
Pedigrees; Genetic linkage analysis; Kinship; Graphics;
D O I
10.1159/000363105
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Background:The kinship2 package is restructured from the previous kinship package. Existing features are now enhanced and new features added for handling pedigree objects. Methods: Pedigree plotting features have been updated to display features on complex pedigrees while adhering to pedigree plotting standards. Kinship matrices can now be calculated for the X chromosome. Other methods have been added to subset and trim pedigrees while maintaining the pedigree structure. Conclusion: We make the kinship2 package available for R on the Contributed R Archives Network (CRAN), where data management is built-in and other packages can use the pedigree object. (C) 2014 S. Karger AG, Basel
引用
收藏
页码:91 / 93
页数:3
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