A large-scale retrospective study of closing-in behavior in Alzheimer's disease

被引:20
|
作者
Ambron, Elisabetta [2 ]
McIntosh, Robert D. [1 ]
Allaria, Francesca [3 ]
Della Sala, Sergio [1 ]
机构
[1] Univ Edinburgh, Dept Psychol, Ctr Cognit Aging & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland
[2] Suor Orsola Benincasa Univ, Expt Psychol Lab, Naples, Italy
[3] Univ Milan, St Paolo Hosp, Neurol Dept 3, Milan, Italy
关键词
Constructional apraxia; Dementia; Attention; Executive functions; Visuospatial abilities; Drawing; ATTRACTION ACCOUNT; DIAGNOSIS; DEMENTIA; CHILDREN; TASK;
D O I
10.1017/S1355617709990245
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The frequency and characteristics of closing-in behavior (CIB) were examined in 797 patients with Alzheimer's disease (AD), 132 of whom were followed up longitudinally. The frequency of CIB increased with the complexity of the graphic copying task and with the severity of Alzheimer's disease. Regression analyses suggested that attentional deficits are critical factors for the appearance of CIB, but that visuospatial impairments also play an important role in the emergence of severe forms of CIB. (JINS, 2009, 15, 787-792.)
引用
收藏
页码:787 / 792
页数:6
相关论文
共 50 条
  • [41] Alzheimer's disease -: Closing in on γ-secretase
    De Strooper, B
    NATURE, 2000, 405 (6787) : 627 - 629
  • [42] Multiple Drug Intolerance Syndrome: A Large-Scale Retrospective Study
    Omer, Hisham M. R. B.
    Hodson, James
    Thomas, Sarah K.
    Coleman, Jamie J.
    DRUG SAFETY, 2014, 37 (12) : 1037 - 1045
  • [43] Large-scale loop-closing with pictorial matching
    Chen, Cheng
    Wang, Han
    2006 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA), VOLS 1-10, 2006, : 1194 - 1199
  • [44] A Large-Scale Study of Mobile Search Examination Behavior
    Wang, Xiaochuan
    Su, Ning
    He, Zexue
    Liu, Yiqun
    Ma, Shaoping
    ACM/SIGIR PROCEEDINGS 2018, 2018, : 1129 - 1132
  • [45] A Study of the Rockfill Material Behavior in Large-Scale Tests
    Ghanbari, A.
    Hamid, A.
    Abdolahzadeh, N.
    CIVIL ENGINEERING INFRASTRUCTURES JOURNAL-CEIJ, 2013, 46 (02): : 125 - 143
  • [46] A Large-Scale Empirical Study of Geotagging Behavior on Twitter
    Huang, Binxuan
    Carley, Kathleen M.
    PROCEEDINGS OF THE 2019 IEEE/ACM INTERNATIONAL CONFERENCE ON ADVANCES IN SOCIAL NETWORKS ANALYSIS AND MINING (ASONAM 2019), 2019, : 365 - 373
  • [47] Multiple Drug Intolerance Syndrome: A Large-Scale Retrospective Study
    Hisham M. R. B. Omer
    James Hodson
    Sarah K. Thomas
    Jamie J. Coleman
    Drug Safety, 2014, 37 : 1037 - 1045
  • [48] A large-scale retrospective study in China explores risk factors for disease severity in plaque psoriasis
    Wang, Huiwei
    Shi, Jialiang
    Hou, Suchun
    Kang, Xiaojing
    Yu, Chen
    Jin, Hongzhong
    Yang, Bin
    Shi, Yuling
    Li, Fuqiu
    Li, Wei
    Gu, Jun
    Lei, Mingjun
    Lin, Youkun
    Dang, Lin
    Lin, Jialin
    Guo, Qing
    Wang, Gang
    Liu, Xiaoming
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [49] Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer's Disease
    Kutzsche, Janine
    Schemmert, Sarah
    Tusche, Markus
    Neddens, Joerg
    Rabl, Roland
    Juergens, Dagmar
    Brener, Oleksandr
    Willuweit, Antje
    Hutter-Paier, Birgit
    Willbold, Dieter
    MOLECULES, 2017, 22 (10)
  • [50] Altered large-scale dynamic connectivity patterns in Alzheimer's disease and mild cognitive impairment patients: A machine learning study
    Jing, Rixing
    Chen, Pindong
    Wei, Yongbin
    Si, Juanning
    Zhou, Yuying
    Wang, Dawei
    Song, Chengyuan
    Yang, Hongwei
    Zhang, Zengqiang
    Yao, Hongxiang
    Kang, Xiaopeng
    Fan, Lingzhong
    Han, Tong
    Qin, Wen
    Zhou, Bo
    Jiang, Tianzi
    Lu, Jie
    Han, Ying
    Zhang, Xi
    Liu, Bing
    Yu, Chunshui
    Wang, Pan
    Liu, Yong
    Alzheimers Dis Neuroimaging Initiat
    HUMAN BRAIN MAPPING, 2023, 44 (09) : 3467 - 3480