An integrated software system for analyzing nanopore data

被引：10

作者：

Zhang, Na ^{[1
,2
]}

Hu, Yong-Xu ^{[2
]}

Gu, Zhen ^{[1
,2
]}

Ying, Yi-Lun ^{[2
]}

He, Pin-Gang ^{[1
]}

Long, Yi-Tao ^{[2
]}

机构：

[1] E China Normal Univ, Dept Chem, Shanghai 200241, Peoples R China

[2] E China Univ Sci & Technol, Dept Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China

来源：

CHINESE SCIENCE BULLETIN | 2014年 / 59卷 / 35期

基金：

中国国家自然科学基金;

关键词：

Nanopore; Data analysis; Integrated software system; beta-Amyloid; 42; SINGLE-MOLECULE; PROTEIN NANOPORE; MEMBRANE-CHANNEL; TRANSLOCATION; DNA; EVENTS;

D O I：

10.1007/s11434-014-0660-4

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We presented an integrated software system for analyzing nanopore data. This self-developed software provided rapid processes for accurate location, classification, and evaluation of every individual blockade. Using the proposed software, statistical analysis could be achieved easily and conveniently. The results of beta-Amyloid 42 demonstrated that our data process could rapidly extract duration time and current amplitudes. In addition, our data process could accurately carry out statistical fittings.

引用

页码：4942 / 4945

页数：4

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