Induction of glutathione S-transferase activity in Triatoma infestans

被引：34

作者：

Sivori, JL

Casabe, N

Zerba, EN

Wood, EJ

机构：

[1] UNIV BUENOS AIRES,FAC CIENCIAS EXACTAS & NAT,RA-1053 BUENOS AIRES,DF,ARGENTINA

[2] CONSEJO NACL INVEST CIENT & TECN,CITEFA,CIPEIN,CTR INVEST PLAGAS & INSECTICIDAS,BUENOS AIRES,DF,ARGENTINA

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 1997年 / 92卷 / 06期

关键词：

Triatoma infestans; glutathione S-transferase; induction;

D O I：

10.1590/S0074-02761997000600013

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infestans resulted in no GST induction. Meanwhile, general insecticide synergist such as piperonyl butoxide (160 mu g/insect) increased the GST-activity in the range of 120-140%. Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.

引用

页码：797 / 802

页数：6

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