Japanese encephalitis The virus and vaccines

被引:193
|
作者
Yun, Sang-Im [1 ]
Lee, Young-Min [1 ]
机构
[1] Utah State Univ, Dept Anim Dairy & Vet Sci, Utah Sci Technol & Res, Coll Agr & Appl Sci, Logan, UT 84322 USA
基金
新加坡国家研究基金会; 美国国家卫生研究院;
关键词
Japanese encephalitis virus; vaccine; immunization; biodefense; prevention; pathogenesis; virulence; flavivirus; WEST-NILE-VIRUS; YELLOW-FEVER VIRUS; ACUTE DISSEMINATED ENCEPHALOMYELITIS; NONSTRUCTURAL PROTEIN NS2A; CYTOTOXIC T-LYMPHOCYTES; LONG-TERM IMMUNITY; DENGUE-VIRUS; PROTECTIVE IMMUNITY; ENVELOPE PROTEIN; NEUTRALIZING ANTIBODY;
D O I
10.4161/hv.26902
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Japanese encephalitis (JE) is an infectious disease of the central nervous system caused by Japanese encephalitis virus (JEV), a zoonotic mosquito-borne flavivirus. JEV is prevalent in much of Asia and the Western Pacific, with over 4 billion people living at risk of infection. In the absence of antiviral intervention, vaccination is the only strategy to develop long-term sustainable protection against JEV infection. Over the past half-century, a mouse brain-derived inactivated vaccine has been used internationally for active immunization. To date, however, JEV is still a clinically important, emerging, and re-emerging human pathogen of global significance. In recent years, production of the mouse brain-derived vaccine has been discontinued, but 3 new cell culture-derived vaccines are available in various parts of the world. Here we review current aspects of JEV biology, summarize the 4 types of JEV vaccine, and discuss the potential of an infectious JEV cDNA technology for future vaccine development.
引用
收藏
页码:263 / 279
页数:17
相关论文
共 50 条
  • [21] Live Chimeric and Inactivated Japanese Encephalitis Virus Vaccines Differ in Their Cross-Protective Values against Murray Valley Encephalitis Virus
    Lobigs, Mario
    Larena, Maximilian
    Alsharifi, Mohammed
    Lee, Eva
    Pavy, Megan
    JOURNAL OF VIROLOGY, 2009, 83 (06) : 2436 - 2445
  • [22] Replicon-based Japanese encephalitis virus vaccines elicit immune response in mice
    Huang, Ying
    Liu, Shan
    Yang, Peng
    Wang, Chao
    Du, Yun
    Yu, Weiyuan
    Sun, Zhiwei
    JOURNAL OF VIROLOGICAL METHODS, 2012, 179 (01) : 217 - 225
  • [23] The suitability of yellow fever and Japanese encephalitis vaccines for immunization against West Nile virus
    Yamshchikov, G
    Borisevich, V
    Kwok, CW
    Nistler, R
    Kohlmeier, J
    Seregin, A
    Chaporgina, E
    Benedict, S
    Yamshchikov, V
    VACCINE, 2005, 23 (39) : 4785 - 4792
  • [24] MHC binding peptides for designing of vaccines against Japanese encephalitis virus: A computational approach
    Sayeed, Usman
    Wadhwa, Gulshan
    Jamal, Qazi Mohd Sajid
    Kamal, Mohammad A.
    Akhtar, Salman
    Siddiqui, Mohd Haris
    Khan, M. Salman
    SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2018, 25 (08) : 1546 - 1551
  • [25] Japanese encephalitis and vaccines: Past and future prospects
    Paulke-Korinek M.
    Kollaritsch H.
    Wiener klinische Wochenschrift, 2008, 120 (Suppl 4) : 15 - 19
  • [26] Current use and development of vaccines for Japanese encephalitis
    Beasley, David W. C.
    Lewthwaite, Penny
    Solomon, Tom
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2008, 8 (01) : 95 - 106
  • [27] Japanese encephalitis: update on vaccines and vaccine recommendations
    Wilder-Smith, A.
    Halstead, S. B.
    CURRENT OPINION IN INFECTIOUS DISEASES, 2010, 23 (05) : 426 - 431
  • [28] SYSTEMIC ALLERGIC REACTIONS TO JAPANESE ENCEPHALITIS VACCINES
    NAZARETH, B
    LEVIN, J
    JOHNSON, H
    BEGG, N
    VACCINE, 1994, 12 (07) : 666 - 666
  • [29] Allergy to IXIARO and BIKEN Japanese Encephalitis Vaccines
    McCallum, Andrew D.
    Jones, Michael E.
    JOURNAL OF TRAVEL MEDICINE, 2013, 20 (01) : 60 - 62
  • [30] PROTECTION AGAINST JAPANESE ENCEPHALITIS BY INACTIVATED VACCINES
    HOKE, CH
    NISALAK, A
    SANGAWHIPA, N
    JATANASEN, S
    LAORAKAPONGSE, T
    INNIS, BL
    KOTCHASENEE, SO
    GINGRICH, JB
    LATENDRESSE, J
    FUKAI, K
    BURKE, DS
    NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (10): : 608 - 614