Radical-mediated thiodesulfonylation of the vinyl sulfones: access to (α-fluoro)vinyl sulfides

被引：33
|
作者：
Sacasa, Pablo R. [1 ]
Zayas, Jessica [1 ]
Wnuk, Stanislaw F. [1 ]
机构：
[1] Florida Int Univ, Dept Chem & Biochem, Miami, FL 33199 USA
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 38期
关键词：
Fluoroalkenes; Radical reactions; Vinyl sulfides; alpha-Fluoro vinyl sulfides; Vinyl sulfones; CROSS-COUPLING REACTION; STEREOSELECTIVE-SYNTHESIS; STEREOSPECIFIC METHOD; HALIDES; HYDROTHIOLATION; INACTIVATION; OLEFINS; ALKYNES; THIOLS; MILD;
D O I：
10.1016/j.tetlet.2009.07.063
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Radical-mediated thiodesulfonylation of the vinyl and (alpha-fluoro)vinyl sulfones, derived from aldehydes and ketones, with aryl thiols in organic or aqueous medium provided access to vinyl and (a-fluoro)vinyl sulfides. The vinyl sulfides were formed predominantly with E stereochemistry independent of the stereochemistry of the starting vinyl sulfones. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5424 / 5427
页数：4
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