Adipocytes affect castration-resistant prostate cancer cells in resistance to cytotoxic action of NK cells through alterations of pd-l1/nkg2d ligand levels

被引:0
|
作者
Xu, Lijun [1 ]
Shen, Mingjing [1 ]
Chen, Xiaodong [2 ]
Zhu, Rongying [2 ]
Yang, Dong-rong [1 ]
Tsai, Ying [2 ]
Keng, Peter [2 ]
Chen, Yuhchyau [2 ]
Lee, Soo Ok [2 ]
机构
[1] Soochow Hosp, Suzhou, Jiangsu, Peoples R China
[2] Univ Rochester, Med Ctr, Rochester, NY 14642 USA
关键词
D O I
10.1158/1538-7445.AM2018-3147
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3147
引用
收藏
页数:2
相关论文
共 27 条
  • [21] Antibody targeting tumor-derived soluble NKG2D ligand sMIC provides dual costimulation of CD8 T cells and enables sMIC plus tumors to respond to PD1/PD-L1 blockade therapy.
    Zhang, Jinyu
    Larrocha, Pablo
    Dhar, Payal
    Wu, Jennifer
    CANCER IMMUNOLOGY RESEARCH, 2020, 8 (03) : 70 - 70
  • [22] Antibody targeting tumor-derived soluble NKG2D ligand sMIC provides dual co-stimulation of CD8 T cells and enables sMIC+ tumors respond to PD1/PD-L1 blockade therapy
    Zhang, Jinyu
    Larrocha, Pablo Saenz-Lopez
    Zhang, Bin
    Wainwright, Derek
    Dhar, Payal
    Wu, Jennifer D.
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7 (01):
  • [23] Contrasting Effects of the Cytotoxic Anticancer Drug Gemcitabine and the EGFR Tyrosine Kinase Inhibitor Gefitinib on NK Cell-Mediated Cytotoxicity via Regulation of NKG2D Ligand in Non-Small-Cell Lung Cancer Cells
    Okita, Riki
    Wolf, Diana
    Yasuda, Koichiro
    Maeda, Ai
    Yukawa, Takuro
    Saisho, Shinsuke
    Shimizu, Katsuhiko
    Yamaguchi, Yoshiyuki
    Oka, Mikio
    Nakayama, Eiichi
    Lundqvist, Andreas
    Kiessling, Rolf
    Seliger, Barbara
    Nakata, Masao
    PLOS ONE, 2015, 10 (10):
  • [24] Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration-resistant prostate cancer cells
    Hsia, Yi-Jan
    Lin, Zhang-Min
    Zhang, Taolan
    Chou, Tz-Chong
    ONCOLOGY REPORTS, 2024, 51 (05)
  • [25] Programmed Death Ligand-1 (PD-L1) Regulated by NRF-2/MicroRNA-1 Regulatory Axis Enhances Drug Resistance and Promotes Tumorigenic Properties in Sorafenib-Resistant Hepatoma Cells
    Li, Dong
    Sun, Fei-fan
    Wang, Dan
    Wang, Tao
    Peng, Jing-jing
    Feng, Jian-Qiong
    Li, Hua
    Wang, Chao
    Zhou, Dai-jun
    Luo, Hong
    Fu, Zeng-qiang
    Zhang, Tao
    ONCOLOGY RESEARCH, 2020, 28 (05) : 467 - 481
  • [26] β-elemonic acid inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells through the suppression of JAK2/ STAT3/MCL-1 and NF-xB signal pathways
    Bao, Xiaowen
    Zhu, Jianwei
    Ren, Chaoxing
    Zhao, Ang
    Zhang, Mingya
    Zhu, Zhiming
    Lu, Xuanzhao
    Zhang, Yuning
    Li, Xiaotian
    Sima, Xinyu
    Li, Jiaqi
    Zhang, Qi
    Ma, Bo
    CHEMICO-BIOLOGICAL INTERACTIONS, 2021, 342
  • [27] Programmed Death Ligand-1 (PD-L1) Regulated by NRF-2/MicroRNA-1 Regulatory Axis Enhances Drug Resistance and Promotes Tumorigenic Properties in Sorafenib-Resistant Hepatoma Cells (vol 28, pg 467, 2021)
    Li, Dong
    Sun, Fei-fan
    Wang, Dan
    Wang, Tao
    Peng, Jing-jing
    Feng, Jian-Qiong
    Li, Hua
    Wang, Chao
    Zhou, Dai-jun
    Luo, Hong
    Fu, Zeng-qiang
    Zhang, Tao
    ONCOLOGY RESEARCH, 2020, 28 (7-8) : 827 - 828