Epstein-Barr Virus-associated Smooth Muscle Tumors in AIDS Patients: A Largest Case (Series)

被引：20

作者：

Issarachaikul, Ratima ^{[1
]}

Shuangshoti, Shanop ^{[2
]}

Suankratay, Chusana ^{[1
]}

机构：

[1] Chulalongkorn Univ, Dept Med, Div Infect Dis, Bangkok 10330, Thailand

[2] Chulalongkorn Univ, Fac Med, Dept Pathol, Bangkok 10330, Thailand

来源：

INTERNAL MEDICINE | 2014年 / 53卷 / 20期

关键词：

Epstein-Barr virus; smooth muscle tumors; AIDS; HIV; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; NASOPHARYNGEAL; LEIOMYOSARCOMA; MALIGNANCIES; DNA;

D O I：

10.2169/internalmedicine.53.2674

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study aimed to determine the outcomes of Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMTs) in AIDS patients at King Chulalongkorn Memorial Hospital, Bangkok, Thailand, treated from 2001-2011. Of the 17 patients, there were five men with a median CD4 count of 26 cells/mu L. Eight and nine patients had single and multiple sites, respectively. The most common site was the cranial epidura (58.8%). All patients had EBV within the tumor. Seven patients underwent surgery. The median follow-up was one year. The mortality rate was 41.2%. All patients with undetectable HIV viremia survived. This is the largest case series regarding EBV-associated SMTs in AIDS patients with a long follow-up period.

引用

页码：2391 / 2396

页数：6

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