Neutron capture autoradio graphic study of the biodistribution of 10B in tumor-bearing mice

被引：9

作者：

Ogura, K

Yanagie, H

Eriguchi, M

Lehmann, EH

Kühne, G

Bayon, G

Kobayashi, H

机构：

[1] Nihon Univ, Coll Ind Technol, High Technol Res Ctr, Narashino, Chiba 2750005, Japan

[2] Univ Tokyo, Res Ctr Adv Sci & Technol, Meguro Ku, Tokyo 1538904, Japan

[3] Paul Scherrer Inst, Dept Spallat Neutron Source, CH-5232 Villigen, Switzerland

[4] CEA, SIREN, DRE SRO, F-91191 Gif Sur Yvette, France

[5] Rikkyo Univ, Inst Atom Energy, Yokosuka, Kanagawa 24001, Japan

来源：

APPLIED RADIATION AND ISOTOPES | 2004年 / 61卷 / 04期

关键词：

boron neutron capture therapy; neutron capture alpha-autoradiography; CR-39; cold neutron; thermal neutron; PEW etching solution;

D O I：

10.1016/j.apradiso.2004.03.084

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

For the study on boron neutron capture therapy, the whole-body sections of tumor-bearing mice infused with B-10 attached to CR-39 plastic track detectors were exposed to thermal and cold neutron beams. Neutron capture autoradiographic images obtained by the cold neutron irradiation were extremely superior in quality to those of the thermal neutron beams. From the autoradiographic images, the B-10 reaction dose of the neutron-induced particles was estimated using the differential LET distribution. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：585 / 590

页数：6

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