Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy

被引：81

作者：

Malaguarnera, Giulia ^{[1
]}

Gagliano, Caterina ^{[2
]}

Giordano, Maria ^{[3
]}

Salomone, Salvatore ^{[1
,4
]}

Vacante, Marco ^{[3
]}

Bucolo, Claudio ^{[1
,4
]}

Caraci, Filippo ^{[1
,5
,6
]}

Reibaldi, Michele ^{[2
]}

Drago, Filippo ^{[1
,4
]}

Avitabile, Teresio ^{[2
]}

Motta, Massimo ^{[3
]}

机构：

[1] Univ Catania, Int Ph D Programme Neuropharmacol, I-95123 Catania, Italy

[2] Univ Catania, Dept Ophthalmol, I-95123 Catania, Italy

[3] Univ Catania, Res Ctr Great Senescence, I-95125 Catania, Italy

[4] Univ Catania, Dept Clin & Mol Biomed, Sect Pharmacol & Biochem, I-95125 Catania, Italy

[5] IRCCS, Oasi Maria SS Inst Res Mental Retardat & Brain Ag, I-94018 Troina, Italy

[6] Univ Catania, Dept Educ Sci, I-95124 Catania, Italy

来源：

BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷

关键词：

PLASMA; MELLITUS; HYPERHOMOCYSTEINEMIA;

D O I：

10.1155/2014/191497

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients.

引用

页数：4

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