Disturbances of saccadic eye movements in monkeys during development of MPTP-induced syndrome

被引：2

作者：

Tereshchenko, LV ^{[1
]}

Yudin, AG ^{[1
]}

Kuznetsov, YB ^{[1
]}

Latanov, AV ^{[1
]}

Shul'govskii, VV ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Dept Higher Nervous Act, Moscow 117234, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2002年 / 133卷 / 02期

关键词：

idiopathic parkinsonism; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; saccade; monkey;

D O I：

10.1023/A:1015563225510

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-Induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP- syndrome. Different disturbances of large- and small-scale saccades were found.

引用

页码：182 / 184

页数：3

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