A Water-Soluble Copper(II) Complex for the Selective Fluorescence Detection of Nitric Oxide/Nitroxyl and Imaging in Living Cells

被引：32

作者：

Sun, Xiaolong ^{[1
]}

Kim, Gyoungmi ^{[2
]}

Xu, Yufang ^{[3
]}

Yoon, Juyoung ^{[2
]}

James, Tony D. ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea

[3] E China Univ Sci & Technol, Sch Pharm, Meilong Rd 130, Shanghai 200237, Peoples R China

来源：

CHEMPLUSCHEM | 2016年 / 81卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

cell imaging; copper; fluorescence probes; nitric oxide; nitroxyl; DEHYDROASCORBIC ACID; OXIDE PRODUCTION; AQUEOUS-SOLUTION; PROBE; 4,5-DIAMINOFLUORESCEIN; NITROXYL; SENSITIVITY; SYSTEM; NO;

D O I：

10.1002/cplu.201500436

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel water-soluble copper(II) naphthalimide complex fluorescent probe was devised and displayed significant fluorescence turn-on response for nitric oxide and nitroxyl over other biologically relevant reactive oxygen species under physiological conditions. The dual-analyte recognition of this simple and sensitive probe was successfully applied for the imaging of exogenous and endogenous NO and HNO in living cells.

引用

页码：30 / 34

页数：5

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