Relief of cannabis withdrawal symptoms and cannabis quitting strategies in people with schizophrenia

被引:5
|
作者
Koola, Maju Mathew [1 ,2 ]
Boggs, Douglas Lee [1 ,3 ]
Kelly, Deanna Lynn [1 ]
Liu, Fang [1 ]
Linthicum, Jared Allen [1 ]
Turner, Hailey Elaine [1 ]
McMahon, Robert Patrick [1 ]
Gorelick, David Alan [4 ]
机构
[1] Univ Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21201 USA
[2] Sheppard Pratt Hlth Syst, Clin Res Programs, Baltimore, MD USA
[3] Yale Univ, Sch Med, Dept Psychiat, Vet Affairs Connecticut Healthcare Syst, New Haven, CT USA
[4] NIDA, Chem & Drug Metab Sect, Intramural Res Program, NIH, Baltimore, MD 21224 USA
基金
美国国家卫生研究院;
关键词
Schizophrenia; Cannabis; Drug withdrawal symptoms; Coping behavior; Abstinence; SUBSTANCE USE DISORDERS; SERIOUS MENTAL-ILLNESS; MARIJUANA USE; NICOTINE DEPENDENCE; ABSTINENCE SYMPTOMS; POPULATION; PSYCHOSIS; TOBACCO; ABUSE; ONSET;
D O I
10.1016/j.psychres.2013.07.044
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
This study examined the response to cannabis withdrawal symptoms and use of quitting strategies to maintain abstinence in people with schizophrenia. A convenience sample of 120 participants with schizophrenia who had at least weekly cannabis use and a previous quit attempt without formal treatment were administered the 176-item Marijuana Quit Questionnaire to characterize their "most serious" (self-defined) quit attempt. One hundred thirteen participants had withdrawal symptoms, of whom 104 (92.0%) took some action to relieve a symptom, most commonly nicotine use (75%). 90% of withdrawal symptoms evoked an action for relief in a majority of participants experiencing them, most frequently anxiety (95.2% of participants) and cannabis craving (94.4%). 96% of participants used one or more quitting strategies to maintain abstinence during their quit attempt, most commonly getting rid of cannabis (72%) and cannabis paraphernalia (67%). Religious support or prayer was the quitting strategy most often deemed "most helpful" (15%). Use of a self-identified most helpful quitting strategy was associated with significantly higher one-month (80.8% vs. 73.6%) and one-year (54.9% vs. 41.3%) abstinence rates. Actions to relieve cannabis withdrawal symptoms in people with schizophrenia are common. Promotion of effective quitting strategies may aid relapse prevention. Published by Elsevier Ireland Ltd.
引用
收藏
页码:273 / 278
页数:6
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