The Probability of Being in Response (PBR): A Novel Efficacy Endpoint for Chronic Graft Versus Host Disease (GvHD) Applied to the Reach-3 Study of Ruxolitinib Versus BAT

被引：0
|
作者：
Hollaender, Norbert [1 ]
Glimm, Ekkehard [1 ]
Gauvin, Jennifer [2 ]
Stefanelli, Tommaso [1 ]
Zeiser, Robert [3 ]
机构：
[1] Novartis Pharma AG, Basel, Switzerland
[2] Novartis Pharmaceut, E Hanover, NJ USA
[3] Univ Freiburg, Fac Med, Med Ctr, Dept Med 1, Freiburg, Germany
来源：
BLOOD | 2022年 / 140卷
关键词：
D O I：
10.1182/blood-2022-159432
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：10521 / 10522
页数：2
相关论文
共 50 条
  • [41] Design and Patient Characteristics of the Chronic Graft-versus-Host Disease Response Measures Validation Study
    Lee, Stephanie J.
    Flowers, Mary E. D.
    Storer, Barry
    Onstad, Lynn
    Kurukulasuriya, Chareeni
    Jagasia, Madan
    Hamilton, Betty
    Chen, George
    Cutler, Corey
    Broady, Raewyn
    Arora, Mukta
    Pidala, Joseph
    Alousi, Amin
    Arai, Sally
    Sarantopoulos, Stefanie
    Jaglowski, Samantha
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2018, 24 (08) : 1727 - 1732
  • [42] Ruxolitinib for pediatric patients with treatment-naive and steroid-refractory acute graft-versus-host disease: the REACH4 study
    Locatelli, Franco
    Kang, Hyoung Jin
    Bruno, Benedicte
    Gandemer, Virginie
    Rialland, Fanny
    Faraci, Maura
    Takahashi, Yoshiyuki
    Koh, Katsuyoshi
    Bittencourt, Henrique
    Cleary, Grace
    Rosko, Christine
    Li, Xuechan
    St Pierre, Annie
    Prahallad, Anirudh
    Diaz-de-Heredia, Cristina
    BLOOD, 2024, 144 (20) : 2095 - 2106
  • [43] Early Versus Late Treatment with Ruxolitinib in Patients with Steroid-Refractory Acute Graft-Versus-Host Disease: A Post Hoc Analysis from the Randomized Phase 3 REACH2 Study
    Socie, Gerard
    Xue, Zhenyi
    Bhatt, Valkal
    Galvin, John
    Mohty, Mohamad
    BLOOD, 2022, 140 : 4765 - 4766
  • [44] An exaggerated B cell CpG response in human chronic graft-versus-host disease: A potential mechanism and biomarker for diagnosis of chronic GVHD.
    She, K
    Gilman, AL
    Schultz, KR
    BLOOD, 2004, 104 (11) : 323B - 323B
  • [45] Study Protocol: Predicting the Quality of Response to Specific Treatments (PQRST) in Chronic Graft-versus-Host Disease
    Hamilton, Betty K.
    Onstad, Lynn
    Carpenter, Paul A.
    Pidala, Joseph
    El Jurdi, Najla
    Farhadfar, Nosha
    Kitko, Carrie L.
    Lee, Catherine J.
    Mehta, Rohtesh
    Chen, George L.
    Cutler, Corey
    Lee, Stephanie J.
    CONTEMPORARY CLINICAL TRIALS, 2024, 145
  • [46] Prospective Longitudinal Study of Late Acute Graft Versus Host Disease after Hematopoietic Cell Transplantation: A Report from Chronic GVHD Consortium
    Khera, Nandita
    Chai, Xiaoyu
    Duong, Hien K.
    Inamoto, Yoshihiro
    Chen, George L.
    Mayer, Sebastian
    Arora, Mukta
    Palmer, Jeanne
    Flowers, Mary E. D.
    Cutler, Corey S.
    Lukezw, Alexander
    Arai, Sally
    Lazaryan, Aleksandr
    Jagasia, Madan H.
    Pusic, Iskra
    Wood, William
    Lee, Stephanie J.
    Pidala, Joseph
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2015, 21 (02) : S336 - S337
  • [47] Prospective Longitudinal Study of Late Acute Graft Versus Host Disease after Hematopoietic Cell Transplantation: A Report from Chronic GVHD Consortium
    Khera, N.
    Chai, X.
    Duong, H.
    Inamoto, Y.
    Chen, G.
    Mayer, S.
    Arora, M.
    Palmer, J.
    Flowers, M.
    Cutler, C.
    Lukez, A.
    Arai, S.
    Lazaryan, A.
    Pusic, I.
    Krupski, M. C.
    Wood, W.
    Lee, S.
    Pidala, J.
    BONE MARROW TRANSPLANTATION, 2015, 50 : S384 - S385
  • [48] Experimental study of human gingival tissue-derived mesenchymal stem cells in management of chronic Graft-Versus-Host Disease (GVHD)
    Jian, G.
    Lu, L.
    Lu, Y.
    Ru, H.
    TRANSPLANTATION, 2018, 102 : 105 - 105
  • [49] Safety and Efficacy of Axatilimab at 3 Different Doses in Patients with Chronic Graft-Versus-Host Disease (AGAVE-201)
    Wolff, Daniel
    Cutler, Corey
    Lee, Stephanie J.
    Pusic, Iskra
    Bittencourt, Henrique
    White, Jennifer
    Hamadani, Mehdi
    Arai, Sally
    Salhotra, Amandeep
    Perez-Simon, Jose A.
    Alousi, Amin
    Choe, Hannah
    Kwon, Mi
    Bermudez, Arancha
    Kim, Inho
    Socie, Gerard
    Radojcic, Vedran
    O'Toole, Timothy
    Tian, Chuan
    Ordentlich, Peter
    DeFilipp, Zachariah
    Kitko, Carrie L.
    BLOOD, 2023, 142
  • [50] Efficacy of low-dose Ruxolitinib as Savage Therapy in Heavily Pretreated Patients with Moderate/severe steroid-refractory Chronic graft-versus-host Disease
    Zhao, Yanmin
    Shi, Jimin
    Luo, Yi
    Tan, Yamin
    Yu, Jian
    Fu, Huarui
    Lai, Xiaoyu
    Huang, He
    BONE MARROW TRANSPLANTATION, 2020, 55 (SUPPL 1) : 344 - 344
12345