Computational methods for predicting intramolecular G-quadruplexes in nucleotide sequence

被引:0
|
作者
D'Antonio, L [1 ]
Bagga, P [1 ]
机构
[1] Ramapo Coll, Dept Comp Sci, Mahwah, NJ USA
来源
2004 IEEE COMPUTATIONAL SYSTEMS BIOINFORMATICS CONFERENCE, PROCEEDINGS | 2004年
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Guanine-rich sequences, including those that form G-quadruplexes, are abundant in regions of biological significance. In order to map putative G-quadruplex elements within mammalian genes we have created a suite of computational tools. This suite contains algorithms to search genes for occurrences of the G-quadruplex motif and determine their distribution near RNA processing sites.
引用
收藏
页码:590 / 591
页数:2
相关论文
共 50 条
  • [11] Intramolecular G-quadruplexes formed by d(GT)12 microsatellite sequence in the presence of K+
    Kaluzhny, D. N.
    Bondarev, Ph. S.
    Shchyolkina, A. K.
    Livshits, M. A.
    Borisova, O. F.
    MOLECULAR BIOLOGY, 2008, 42 (04) : 616 - 622
  • [12] Computational and Experimental Characterization of rDNA and rRNA G-Quadruplexes
    Green, Adam T.
    Pickard, Amanda J.
    Li, Rongzhong
    MacKerell, Alexander D., Jr.
    Bierbach, Ulrich
    Cho, Samuel S.
    JOURNAL OF PHYSICAL CHEMISTRY B, 2022, 126 (03): : 609 - 619
  • [13] Polyethylenimine effectively induces, stabilizes, and regulates intramolecular G-quadruplexes
    Sun, Hongxia
    Zhou, Qiuju
    Xiang, Junfeng
    Tang, Yalin
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (16) : 4669 - 4672
  • [14] The stability of intramolecular DNA G-quadruplexes compared with other macromolecules
    Lane, Andrew N.
    BIOCHIMIE, 2012, 94 (02) : 277 - 286
  • [15] Thermodynamic Stability of G-Quadruplexes: Impact of Sequence and Environment
    Jana, Jagannath
    Weisz, Klaus
    CHEMBIOCHEM, 2021, 22 (19) : 2848 - 2856
  • [16] G-Quadruplexes (GQU)
    Haider, Shozeb
    Parkinson, Gary N.
    Marsh, Thomas C.
    JOURNAL OF NUCLEIC ACIDS, 2018, 2018
  • [17] Where the G-quadruplexes are
    Tal Nawy
    Nature Methods, 2015, 12 (9) : 807 - 807
  • [18] G-quadruplexes and helicases
    Mendoza, Oscar
    Bourdoncle, Anne
    Boule, Jean-Baptiste
    Brosh, Robert M., Jr.
    Mergny, Jean-Louis
    NUCLEIC ACIDS RESEARCH, 2016, 44 (05) : 1989 - 2006
  • [19] Hunting G-quadruplexes
    Huppert, J. L.
    BIOCHIMIE, 2008, 90 (08) : 1140 - 1148
  • [20] WHERE THE G-QUADRUPLEXES ARE
    Vogt, Nina
    NATURE METHODS, 2015, 12 (09) : 806 - 807