What is a stem cell niche?

被引:0
|
作者
Nishikawa, S. -I. [1 ]
Osawa, M. [1 ]
机构
[1] Ctr Dev Biol, Chuo Ku, 2-2-3 Minatojima Minami Machi, Kobe, Hyogo 6500047, Japan
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Niche has become the most important issue in stem cell biology, but it is still a hypothetical notion that cannot be defined in a better way than the microenvironment surrounding stem cells. Using a melanocyte stem cell system as a model, we have analyzed the cellular and molecular requirements for differentiation of quiescent stem cells. Our results demonstrate the multiple subsets within the stem cell compartment and thus suggests the complexity of niche.
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页码:1 / +
页数:3
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