Early proximal lung cancer diagnosis and treatment

被引:33
|
作者
McWilliams, A. [1 ,2 ]
Lam, B. [3 ]
Sutedja, T. [4 ]
机构
[1] Univ British Columbia, British Columbia Canc Agcy, Vancouver, BC V5Z 1L3, Canada
[2] Vancouver Gen Hosp, Dept Resp Med, Vancouver, BC, Canada
[3] Univ Hong Kong, Dept Med, Hong Kong, Hong Kong, Peoples R China
[4] VU Acad Med Ctr, Dept Pulm Med, Amsterdam, Netherlands
关键词
SQUAMOUS-CELL CARCINOMA; OPTICAL COHERENCE TOMOGRAPHY; PREINVASIVE BRONCHIAL LESIONS; POSITRON-EMISSION-TOMOGRAPHY; WHITE-LIGHT BRONCHOSCOPY; MALIGNANCY-ASSOCIATED CHANGES; DOSE-RATE BRACHYTHERAPY; AUTOFLUORESCENCE BRONCHOSCOPY; PHOTODYNAMIC THERAPY; SPUTUM CYTOLOGY;
D O I
10.1183/09031936.00124608
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Lung cancer remains the largest cause of cancer deaths worldwide and the overall 5-yr survival rate is only 15%. This is because the majority of the lung cancers are diagnosed at late stages and the treatment outcome is suboptimal. However, the survival of patients with early stage proximal lung cancer is excellent and with advancements in technology we are currently well equipped to diagnose and stage these lung cancers. Together with the application of local bronchoscopic therapeutic modalities that may potentially cure early stage intralluminal lesions, there is expanding interest in the further exploration of new avenues for early detection, localisation, staging, treatment and close surveillance of these high-risk patients who are suffering from chronic field carcinogenesis. The present article will deal with various issues regarding early detection, staging and treatment of centrally located early stage, mostly squamous type, lung cancer.
引用
收藏
页码:656 / 665
页数:10
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