[1] Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham, W Midlands, England
[2] St Georges Univ London, Dept Cardiol, London, England
[3] Boston Univ, Dept Med, Boston, MA 02215 USA
[4] Mt Sinai Med Ctr, New York, NY USA
[5] McMaster Univ, Thrombosis & Atherosclerosis Res Inst, Dept Med, Hamilton, ON L8S 4L8, Canada