RNA polymerase beta' subunit: A target of DNA binding-independent activation

被引：58

作者：

Miller, A

Wood, D

Ebright, RH

RothmanDenes, OB

机构：

[1] UNIV CHICAGO,DEPT MOL GENET & CELL BIOL,CHICAGO,IL 60637

[2] UNIV CHICAGO,DEPT BIOCHEM & MOL BIOL,CHICAGO,IL 60637

[3] RUTGERS STATE UNIV,DEPT CHEM,NEW BRUNSWICK,NJ 08855

[4] RUTGERS STATE UNIV,WAKSMAN INST,NEW BRUNSWICK,NJ 08855

来源：

SCIENCE | 1997年 / 275卷 / 5306期

关键词：

D O I：

10.1126/science.275.5306.1655

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The bacteriophage N4 single-stranded DNA binding protein (N4SSB) activates transcription by the Escherichia coli sigma 70-RNA polymerase at N4 late promoters. Here it is shown that the single-stranded DNA binding activity of N4SSB is not required for transcriptional activation. N4SSB interacts with the carboxyl terminus of the RNA polymerase beta' subunit in a region that is highly conserved in the largest subunits of prokaryotic and eukaryotic RNA polymerases.

引用

页码：1655 / 1657

页数：3

共 50 条

[1] DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
Slagsvold, T
Kraus, I
Fronsdal, K
Saatcioglu, F
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (33) : 31030 - 31036
[2] CONFORMATIONAL CHANGE OF DNA-BINDING SUBUNIT OF RNA POLYMERASE-II ON BINDING TO DNA
HORIKOSHI, M
SEKIMIZU, K
NATORI, S
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 129 (01) : 141 - 147
[3] Interaction with free β′ subunit unmasks DNA-binding domain of RNA polymerase σ subunit
Kulbachinskiy, A
Mustaev, A
Goldfarb, A
Nikiforov, V
FEBS LETTERS, 1999, 454 (1-2) : 71 - 74
[4] Conversion of the ω subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target
Dove, SL
Hochschild, A
GENES & DEVELOPMENT, 1998, 12 (05) : 745 - 754
[5] DNA binding-independent transcriptional activation of the vascular endothelial growth factor gene (VEGF) by the Myb oncoprotein
Lutwyche, Jodi K.
Keough, Rebecca A.
Hunter, Julie
Coles, Leeanne S.
Gonda, Thomas J.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 344 (04) : 1300 - 1307
[6] Activation of the prolactin gene by peroxisome proliferator-activated receptor-α appears to be DNA binding-independent
Tolón, RM
Castillo, AI
Aranda, A
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (41) : 26652 - 26661
[7] BINDING OF RNA POLYMERASE TO DNA
RICHARDSON, JP
JOURNAL OF MOLECULAR BIOLOGY, 1966, 21 (01) : 83 - +
[8] DNA binding-independent induction of IκBα gene transcription by PPARα
Delerive, P
De Bosscher, K
Vanden Berghe, W
Fruchart, JC
Haegeman, G
Staels, B
MOLECULAR ENDOCRINOLOGY, 2002, 16 (05) : 1029 - 1039
[9] DNA-binding determinants of the alpha subunit of RNA polymerase: Novel DNA-binding domain architecture
Gaal, T
Ross, W
Blatter, EE
Tang, H
Jia, X
Krishnan, VV
AssaMunt, N
Ebright, RH
Gourse, RL
GENES & DEVELOPMENT, 1996, 10 (01) : 16 - 26
[10] Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity
Friedman, Meyer J.
Wang, Chuan-En
Li, Xiao-Jiang
Li, Shihua
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (13) : 8283 - 8290

← 1 2 3 4 5 →