Antigenotoxic and Antioxidant Activities of Fruit Extracts from (Tunisian) Pistacia Lentiscus

被引：4
|
作者：
Abdelwahed, A. [2 ]
Bhouri, W. [2 ]
Neffati, A. [2 ]
Ben Sghaier, M. [2 ]
Boubaker, J. [2 ]
Bouhlel, I. [2 ]
Skandrani, I. [2 ]
Ben Ammar, R. [2 ]
Ghedira, K. [2 ]
Chekir-Ghedira, L. [1 ]
机构：
[1] Fac Med Dent, Lab Biol Mol & Cellulaire, Monastir 5000, Tunisia
[2] Fac Pharm, Unite Pharmacognosie Biol Mol UR 99 07 03, Monastir 5000, Tunisia
来源：
FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL | 2009年 / 15卷 / 03期
关键词：
Pistacia lentiscus; SOS chromotest; mutagenic effect; antimutagenic activity; antioxidant activity; MEDICINAL-PLANTS; PHENOLIC-COMPOUNDS; XANTHINE-OXIDASE; SOS CHROMOTEST; MUTAGENICITY; FLAVONOIDS; CARCINOGENESIS; INHIBITORS; FRACTIONS; NETWORK;
D O I：
10.1177/1082013208339705
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Genotoxic and antigenotoxic activities against direct acting mutagen nifuroxazide, and indirect acting genotoxin aflatoxine B1 (AFB1) of extracts prepared from fruits of Pistacia lentiscus, were studied using the SOS chromotest with Escherichia coli PQ 37 as a tester organism. It was found that different extracts showed no genotoxicity when tested with E. coli PQ 37 strain either with or without microsomal extract. On the other hand, our results showed that ethyl acetate fraction and total oligomers flavonoids (TOF) extract obtained from P. lentiscus significantly decreased the genotoxicicity induced by AFB1 (10 mu g/assay) and nifuroxazide (20 mu g/assay). In addition to antigenotoxic activity, these extracts showed an important free radical scavenging activity towards the 2,2-diphenyl-2-picrylhydrazyl (DPPH) free radical and an important antioxidant activity using xanthine/xanthine oxidase system.
引用
收藏
页码：215 / 222
页数：8
相关论文
共 50 条
  • [21] Antioxidant, genotoxic and antigenotoxic activities of daphne gnidium leaf extracts
    Fadwa Chaabane
    Jihed Boubaker
    Amira Loussaif
    Aicha Neffati
    Somaya Kilani-Jaziri
    Kamel Ghedira
    Leila Chekir-Ghedira
    BMC Complementary and Alternative Medicine, 12
  • [22] VOLATILE COMPONENTS OF THE FRUIT OF PISTACIA-LENTISCUS
    WYLLIE, SG
    BROPHY, JJ
    SARAFIS, V
    HOBBS, M
    JOURNAL OF FOOD SCIENCE, 1990, 55 (05) : 1325 - 1326
  • [23] Antioxidant, genotoxic and antigenotoxic activities of daphne gnidium leaf extracts
    Chaabane, Fadwa
    Boubaker, Jihed
    Loussaif, Amira
    Neffati, Aicha
    Kilani-Jaziri, Somaya
    Ghedira, Kamel
    Chekir-Ghedira, Leila
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012, 12
  • [24] Diversity of Sterol Composition in Tunisian Pistacia lentiscus Seed Oil
    Mezni, Faten
    Labidi, Arbia
    Khouja, Mohamed Larbi
    Martine, Lucy
    Berdeaux, Olivier
    Khaldi, Abdelhamid
    CHEMISTRY & BIODIVERSITY, 2016, 13 (05) : 544 - 548
  • [25] Biological properties of extracts from the mixture of honey and berries of Pistacia lentiscus
    Ayad, Rabha
    Amessis-Ouchemoukh, Nadia
    Otmani, Amar
    Guenaoui, Nawel
    Sadou, Dyhia
    Madani, Khodir
    Ouchemoukh, Salim
    NUTRITION AND HEALTH, 2025, 31 (01) : 321 - 330
  • [26] Valorization of Pistacia lentiscus extracts from Morocco: phytochemistry and antibacterial activity
    Hayani, Mouhcine
    Byadi, Said
    Benabbouha, Tariq
    Kachmar, Mohamed Reda
    Chafi, Mohammed
    Aboulmouhajir, Aziz
    Touriya, Zair
    PLANT BIOSYSTEMS, 2024, 158 (01): : 201 - 209
  • [27] Fatty acid composition and antioxidant activity of Pistacia lentiscus L. fruit fatty oil from Algeria
    N. Belyagoubi-Benhammou
    L. Belyagoubi
    A. El Zerey-Belaskri
    A. Zitouni
    N. Ghembaza
    H. Benhassaini
    F. Atik-Bekkara
    A. Piras
    D. Falconieri
    A. Rosa
    Journal of Food Measurement and Characterization, 2018, 12 : 1408 - 1412
  • [28] Antibacterial and antioxidant activities of Pistacia lentiscus essential oils: Impact of total phenolic content on antioxidant efficacy
    Bouchfara, Amin
    Zerrad, Hamass
    Ez-zari, Ayoub
    Laglaoui, Amin
    Nechar, Mounir
    Souhail, Badredine
    BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, 2025, 64
  • [29] Fatty acid composition and antioxidant activity of Pistacia lentiscus L. fruit fatty oil from Algeria
    Belyagoubi-Benhammou, N.
    Belyagoubi, L.
    El Zerey-Belaskri, A.
    Zitouni, A.
    Ghembaza, N.
    Benhassaini, H.
    Atik-Bekkara, F.
    Piras, A.
    Falconieri, D.
    Rosa, A.
    JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, 2018, 12 (02) : 1408 - 1412
  • [30] Comparison of Phytochemical Composition, Antibacterial, and Antifungal Activities of Extracts from Three Organs of Pistacia lentiscus from Saudi Arabia
    Al-Zaben, Maha
    Al Zaban, Mayasar
    Naghmouchi, Souheila
    Alsaloom, Albandary Nasser
    Al-Sugiran, Nada
    Alrokban, Ahlam
    MOLECULES, 2023, 28 (13):
12345