No association between synapsin III gene promoter polymorphisms and multiple sclerosis in German patients

被引：7
|
作者：
Akkad, Denis A. [1 ]
Goedde, Rene [1 ]
Epplen, Joerg T. [1 ]
机构：
[1] Human Genet Ruhr Univ, D-44801 Bochum, Germany
来源：
JOURNAL OF NEUROLOGY | 2006年 / 253卷 / 10期
关键词：
synapsin III; multiple sclerosis; SYN3; association study;
D O I：
10.1007/s00415-006-0214-z
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We investigated whether the polymorphisms rs133946 and rs133945 in the promoter region of the synapsin III (SYN3) gene are associated with multiple sclerosis in German patients. Association of the SYN3 variations and haplotypes with MS is not evident in German MS patients - in contrast to a MS cohort from Italy, as reported previously. © 2006 Steinkopff Verlag.
引用
收藏
页码：1365 / 1366
页数：2
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