High-Throughput crystallographic fragment screening for drug discovery

被引:0
|
作者
Metz, Alexander [1 ]
Huschinann, Franziska [2 ]
Schiebel, Johannes [1 ]
Mueller, Utiye [2 ]
Weiss, Manfred [2 ]
Heine, Andreas [1 ]
Melte, Gerhard [1 ]
机构
[1] Philipps Univ Marburg, Inst Pharmaceut Chem, Marburg, Germany
[2] Helmholtz Zentrum Berlin, Electron Storage Ring BESSY 2, Inst Soft Matter & Funct Mat, Macromol Crystallog HZ BMX, Berlin, Germany
关键词
Fragments; Structure-Based Drug Discovery; Computer-Aided Drug Discovery;
D O I
10.1107/S2053273318094846
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
MS05-O4
引用
收藏
页码:E24 / E24
页数:1
相关论文
共 50 条
  • [21] Cloud computing platform for high-throughput virtual screening and drug discovery
    Wein, Samuel
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [22] Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening
    Sklar, Larry A.
    Carter, Mark B.
    Edwards, Bruce S.
    CURRENT OPINION IN PHARMACOLOGY, 2007, 7 (05) : 527 - 534
  • [23] Fluorescence polarization assays in high-throughput screening and drug discovery: a review
    Hall, Matthew D.
    Yasgar, Adam
    Peryea, Tyler
    Braisted, John C.
    Jadhav, Ajit
    Simeonov, Anton
    Coussens, Nathan P.
    METHODS AND APPLICATIONS IN FLUORESCENCE, 2016, 4 (02):
  • [24] High-throughput kinetics in drug discovery
    Pinto, Maria Filipa
    Sirina, Julija
    Holliday, Nicholas D.
    Mcwhirter, Claire L.
    SLAS DISCOVERY, 2024, 29 (05)
  • [25] High throughput screening in drug discovery
    Carnero A.
    Clinical and Translational Oncology, 2006, 8 (7) : 482 - 490
  • [26] Pooling in high-throughput drug screening
    Kainkaryam, Raghunandan M.
    Woolf, Peter J.
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2009, 12 (03) : 339 - 350
  • [27] Experimental identification of protein-ligand interactions in fragment-based drug discovery with high-throughput protein crystallography screening of fragment libraries
    Das, Debanu
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [28] High-Throughput Screening of Biodiversity for Antibiotic Discovery
    Terekhov, S. S.
    Osterman, I. A.
    Smirnov, I. V.
    ACTA NATURAE, 2018, 10 (03): : 23 - 29
  • [29] High-Throughput Screening for the Discovery of Enzyme Inhibitors
    Lloyd, Matthew D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (19) : 10742 - 10772