Effect of cilazapril and hydrochlorothiazide on mitral regurgitation in patients with essential hypertension with left ventricular hypertrophy. Magnetic resonance tomography data

被引:0
|
作者
Yurpolskaya, LA
Sinitsin, VE
Stukalova, OV
KaganPonomarev, MY
Vilchinskaya, MY
Karpov, YA
机构
关键词
hypertension; treatment; magnetic resonance imaging; angiotensin converting enzyme inhibitors; diuretics;
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R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Mild to moderate mitral regurgitation was revealed by magnetic resonance imaging in 27 of 55 patients (47%) included into randomized double blind placebo controlled comparative trial of cilazapril (5 mg/day) versus hydrochlorothiazide (50 mg/day) in patients with hypertension and left ventricular hypertrophy. Duration of treatment was 6 months. Both drugs caused pronounced lowering of systolic and diastolic blood pressures. Decrease of volume and extent of regurgitation independent of hypotensive eff ect was observed in diuretic-treated patients.
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页码:13 / 17
页数:5
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