PEPTIDES BALANCING BETWEEN TWO RECEPTOR TYPES AND BETWEEN AGONISM AND INVERSE AGONISM IN CONTROLLING APPETITE AND BODY WEIGHT

被引：0
|
作者：
Schwartz, T. W. [1 ,2 ]
Elling, C. E. [2 ]
Jorgensen, R. [2 ]
Holst, B. [1 ]
Beck-Sickinger, A. [3 ]
Hjorth, S. A. [1 ]
Frimurer, T. M. [2 ]
机构：
[1] Univ Copenhagen, Mol Pharmacol Lab, DK-2200 Copenhagen, Denmark
[2] 7TM Pharma AS, Horsholm, Denmark
[3] Univ Leipzig, Inst Biochem, Fac Biosci Pharm & Phsycol, D-04103 Leipzig, Germany
来源：
BIOPOLYMERS | 2009年 / 92卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：305 / 305
页数：1
相关论文
共 50 条
  • [11] Co-agonism between glutamate and glycine on the NMDA receptor - Does it influence the estimation of antagonist dissociation constant?
    Fina, P
    Corsi, M
    Carignani, C
    Trist, DG
    RECEPTOR CLASSIFICATION: THE INTEGRATION OF OPERATIONAL, STRUCTURAL, AND TRANSDUCTIONAL INFORMATION, 1997, 812 : 184 - 186
  • [12] Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gain
    Fukuyama, Kouji
    Motomura, Eishi
    Shiroyama, Takashi
    Okada, Motohiro
    BIOMEDICINE & PHARMACOTHERAPY, 2022, 148
  • [13] GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease
    Sachs, Stephan
    Goetz, Anna
    Finan, Brian
    Feuchtinger, Annette
    DiMarchi, Richard D.
    Doering, Yvonne
    Weber, Christian
    Tschoep, Matthias H.
    Mueller, Timo D.
    Hofmann, Susanna M.
    CARDIOVASCULAR DIABETOLOGY, 2023, 22 (01)
  • [14] THE INVERSE RELATIONSHIP BETWEEN TOBACCO USE AND BODY-WEIGHT
    GRUNBERG, NE
    RESEARCH ADVANCES IN ALCOHOL AND DRUG PROBLEMS, 1990, 10 : 273 - 315
  • [15] The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
    Willson, TM
    Cobb, JE
    Cowan, DJ
    Wiethe, RW
    Correa, ID
    Prakash, SR
    Beck, KD
    Moore, LB
    Kliewer, SA
    Lehmann, JM
    JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (03) : 665 - 668
  • [16] FURTHER EVIDENCE OF AN INVERSE RELATION BETWEEN BODY WEIGHT AND FECUNDITY IN RATS
    CARLSON, AJ
    HOELZEL, F
    FEDERATION PROCEEDINGS, 1951, 10 (01) : 24 - 24
  • [17] Comparison of the brain weight in function of the body weight, between the two sexes
    Dubois, E
    PROCEEDINGS OF THE KONINKLIJKE AKADEMIE VAN WETENSCHAPPEN TE AMSTERDAM, 1919, 21 (6/10): : 850 - 869
  • [18] Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors
    Li, Xiang
    Anderson, Marie
    Collin, Delphine
    Muegge, Ingo
    Wan, John
    Brennan, Debra
    Kugler, Stanley
    Terenzio, Donna
    Kennedy, Charles
    Lin, Siqi
    Labadia, Mark E.
    Cook, Brian
    Hughes, Robert
    Farrow, Neil A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (28) : 11618 - 11630
  • [19] Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the inverse agonism of MPEP
    Malherbe, Pari
    Kratochwil, Nicole
    Muehlemann, Andreas
    Zenner, Marie-Therese
    Fischer, Christophe
    Stahl, Martin
    Gerber, Paul R.
    Jaeschke, Georg
    Porter, Richard H. P.
    JOURNAL OF NEUROCHEMISTRY, 2006, 98 (02) : 601 - 615
  • [20] Novel approach for the quantitative description of 5-HT1A receptor agonism in vivo:: Differentiation between full, partial and silent agonists
    Zuideveld, KP
    Treijtel, N
    Rusic-Pavletic, J
    van der Graaf, PH
    Danhof, M
    BRITISH JOURNAL OF PHARMACOLOGY, 2000, 129 : U26 - U26
12345