Synthesis and Biological Activity of 1,2,4-Triazole Thioether Derivatives Containing Pyrazole Moiety

被引：31
|
作者：
Zhai, Zhiwen [1 ]
Wang, Qiao [1 ]
Shen, Zhonghua [1 ]
Tan, Chengxia [1 ]
Weng, Jianquan [1 ]
Liu, Xinghai [1 ]
机构：
[1] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Zhejiang, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 37卷 / 01期
关键词：
pyrazole; 1,2,4-triazole; synthesis; fungicidal activity; herbicidal activity; ONE-POT SYNTHESIS; DIMERIC CRYSTAL-STRUCTURE; ANTIFUNGAL ACTIVITY; FACILE; DFT;
D O I：
10.6023/cjoc201607031
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of novel 1,2,4-triazole derivatives were synthesized from ethyl trifluoroacetoacetate, triethyl orthoformate, methylhydrazine, phenyl isothiocyanate by multi-step reactions. Their structures were characterized by H-1 NMR, C-13 NMR, HRMS and X-ray diffraction. The target compounds were evaluated for their fungicidal activity and herbicidal activitiy. The results indicated that some of the title compounds displayed certain fungicidal activities against Colletotrichum orbiculare and herbicidal activity against dicotyledons.
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页码：232 / 236
页数：5
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