INHIBITION OF TGF-β1 ATTENUATES ARTICULAR CARTILAGE DEGENERATION IN MATURE KNEE JOINTS OF MOUSE MODELS OF OSTEOARTHRITIS

被引：2
|
作者：
Li, Y. [1 ,2 ]
Chen, R. [1 ]
Mian, M. [1 ]
Fu, M. [1 ]
Zhao, J. [3 ]
Golshirazian, I. [1 ]
Asbury, B. [1 ]
Xu, L. [1 ,2 ]
机构：
[1] Harvard Univ, Sch Dent Med, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Univ Calif Berkeley, Berkeley, CA 94720 USA
来源：
OSTEOARTHRITIS AND CARTILAGE | 2014年 / 22卷
关键词：
D O I：
10.1016/j.joca.2014.02.054
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
引用
收藏
页码：S17 / S18
页数：2
相关论文
共 50 条
  • [21] Delay in articular cartilage degeneration of the knee joint by the conditional removal of discoidin domain receptor 2 in a spontaneous mouse model of osteoarthritis
    Li, Xiaolong
    Chen, Yi
    Xu, Rui
    Wang, Yan
    Jian, Fan
    Long, Hu
    Lai, Wenli
    ANNALS OF TRANSLATIONAL MEDICINE, 2020, 8 (18)
  • [22] REVERSIBILITY OF IMMOBILIZATION-INDUCED ARTICULAR CARTILAGE DEGENERATION AFTER REMOBILIZATION IN RAT KNEE JOINTS
    Ando, A.
    Suda, H.
    Hagiwara, Y.
    Onoda, Y.
    Chimoto, E.
    Saijo, Y.
    Itoi, E.
    OSTEOARTHRITIS AND CARTILAGE, 2010, 18 : S92 - S93
  • [23] Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
    Zhen, Gehua
    Wen, Chunyi
    Jia, Xiaofeng
    Li, Yu
    Crane, Janet L.
    Mears, Simon C.
    Askin, Frederic B.
    Frassica, Frank J.
    Chang, Weizhong
    Yao, Jie
    Carrino, John A.
    Cosgarea, Andrew
    Artemov, Dmitri
    Chen, Qianming
    Zhao, Zhihe
    Zhou, Xuedong
    Riley, Lee
    Sponseller, Paul
    Wan, Mei
    Lu, William Weijia
    Cao, Xu
    NATURE MEDICINE, 2013, 19 (06) : 704 - +
  • [24] Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
    Gehua Zhen
    Chunyi Wen
    Xiaofeng Jia
    Yu Li
    Janet L Crane
    Simon C Mears
    Frederic B Askin
    Frank J Frassica
    Weizhong Chang
    Jie Yao
    John A Carrino
    Andrew Cosgarea
    Dmitri Artemov
    Qianming Chen
    Zhihe Zhao
    Xuedong Zhou
    Lee Riley
    Paul Sponseller
    Mei Wan
    William Weijia Lu
    Xu Cao
    Nature Medicine, 2013, 19 : 704 - 712
  • [25] Regulation of the Friction Coefficient of Articular Cartilage by TGF-β1 and IL-1β
    DuRaine, Grayson
    Neu, Corey P.
    Chan, Stephanie M. T.
    Komvopoulos, Kyriakos
    June, Ranald K.
    Reddi, A. Hari
    JOURNAL OF ORTHOPAEDIC RESEARCH, 2009, 27 (02) : 249 - 256
  • [26] Reversibility of Immobilization-Induced Articular Cartilage Degeneration after Remobilization in Rat Knee Joints
    Ando, Akira
    Suda, Hideaki
    Hagiwara, Yoshihiro
    Onoda, Yoshito
    Chimoto, Eiichi
    Saijo, Yoshifumi
    Itoi, Eiji
    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 224 (02): : 77 - 85
  • [27] Electroacupuncture improves articular microcirculation and attenuates cartilage hypoxia in a male rabbit model of knee osteoarthritis
    Ma, Weiwei
    Mei, Du
    Juan, Lu
    Xing, Longfei
    Chen, Xilin
    Hu, Tingyao
    Zhu, Wenting
    Guo, Changqing
    JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2024, 14 (04): : 414 - 423
  • [28] Cbfβ Is a Novel Modulator against Osteoarthritis by Maintaining Articular Cartilage Homeostasis through TGF-β Signaling
    Che, Xiangguo
    Jin, Xian
    Park, Na Rae
    Kim, Hee-June
    Kyung, Hee-Soo
    Kim, Hyun-Ju
    Lian, Jane B.
    Stein, Janet L.
    Stein, Gary S.
    Choi, Je-Yong
    CELLS, 2023, 12 (07)
  • [29] Genetic Inhibition of FGFR1 in Cartilage at Adult stage Attenuates the Degeneration of Articular Cartilage in FGFR3 disruption mice
    Xie, Yangli
    Xu, Wei
    Huang, Junlan
    Du, Xiaolan
    Zhou, Siru
    Chen, Lin
    Wang, Zuqiang
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S81 - S82
  • [30] Cartilage Degeneration and Excessive Subchondral Bone Formation in Spontaneous Osteoarthritis Involves Altered TGF-β Signaling
    Zhao, Weiwei
    Wang, Ting
    Luo, Qiang
    Chen, Yan
    Leung, Victor Y. L.
    Wen, Chunyi
    Shah, Mohammed F.
    Pan, Haobo
    Chiu, KwongYuen
    Cao, Xu
    Lu, William W.
    JOURNAL OF ORTHOPAEDIC RESEARCH, 2016, 34 (05) : 763 - 770
12345