[4+2] Annulation of Donor-Acceptor Cyclopropanes with Acetylenes Using 1,2-Zwitterionic Reactivity

被引：51
|
作者：
Novikov, Roman A. [1 ,2 ]
Tarasova, Anna V. [1 ]
Denisov, Dmitry A. [1 ]
Borisov, Denis D. [1 ]
Korolev, Victor A. [1 ]
Timofeev, Vladimir P. [2 ]
Tomilov, Yury V. [1 ]
机构：
[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia
[2] Russian Acad Sci, Engelhardt Inst Mol Biol, 32 Vavilov St, Moscow 119991, Russia
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 05期
基金：
俄罗斯科学基金会;
关键词：
SUBSTITUTED NAPHTHALENES; REGIOSELECTIVE SYNTHESIS; MEDIATED DIMERIZATION; GRIGNARD-REAGENTS; DERIVATIVES; ACID; LEWIS; DIHYDRONAPHTHALENES; NITROSOARENES; INHIBITORS;
D O I：
10.1021/acs.joc.7b00209
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new process for the [4 + 2] annulation of donor-acceptor cyclopropanes with acetylenes under the effect of anhydrous GaCl3 using 1,2-zwitterion reactivity was elaborated. The reaction opens access to substituted dihydronaphthalenes, naphthalenes, and other fused carbocycles. The direction of the reaction can be efficiently controlled by temperature.
引用
收藏
页码：2724 / 2738
页数：15
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