The expression of Nuclear Factor-κB in a rat model of polycystic ovary syndrome

被引:0
|
作者
Wang, Hui-lan [1 ]
Xu, Xia [1 ]
Zheng, Zhi-qun [1 ]
机构
[1] Fujian Med Univ, Affiliated Union Hosp, Dept Gynecol & Obstet, Fuzhou, Fujian, Peoples R China
来源
关键词
Polycystic ovary syndrome; NF-kappa B; INSULIN-RESISTANCE; WOMEN; RISK; PCOS;
D O I
10.12891/ceog3873.2018
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To discuss the effect of Nuclear Factor-kappa B (NF-kappa B) in poly cystic ovary syndrome (PCOS). Materials and Methods: Thirty female SD rats were divided into a control group (n=15) and a PCOS group (n=15). The expression of NF-kappa B in ovaries of each group was monitored by way of immunohistochemistry and quantitative PCR. Results: The expression of NF-kappa B p65 in ovaries by immunohistochemical and fluorescence quantitative PCR shows no significant difference between the two groups (p> 0.01). Conclusion: The pathogenesis of this research model has no obvious association with NF-kappa B.
引用
收藏
页码:276 / 279
页数:4
相关论文
共 50 条
  • [21] Expression and Significance of Prosaposin (PSAP) in A Rat Model of Letrozole-induced Polycystic Ovary Syndrome
    Yuan-yuan FANG
    Yi-ning LI
    Ying-xin YE
    Xiu-xia WANG
    Journal of Reproduction and Contraception, 2013, (02) : 67 - 75
  • [22] Regulation of Adiponectin Secretion by Adipocytes in the Polycystic Ovary Syndrome: Role of Tumor Necrosis Factor-α
    Chazenbalk, Gregorio
    Trivax, Bradley S.
    Yildiz, Bulent O.
    Bertolotto, Cristina
    Mathur, Ruchi
    Heneidi, Saleh
    Azziz, Ricardo
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (02): : 935 - 942
  • [23] Effect of cordycep polysaccharide on expression of tumor necrosis factor-α and activity of nuclear factor-κB of hepatic stellate cells in rat
    Yan, Ji-Li
    Li, Hua
    Fan, Yu
    Zhang, Jin-Sheng
    Huang, Fu-Chun
    Fudan University Journal of Medical Sciences, 2003, 30 (01): : 27 - 29
  • [24] Expression of nuclear factor-κB and IκBα proteins in prostatic adenocarcinomas:: Correlation of nuclear factor-κB immunoreactivity with disease recurrence
    Ross, JS
    Kallakury, BVS
    Sheehan, CE
    Fisher, HAG
    Kaufman, RP
    Kaur, P
    Gray, K
    Stringer, B
    CLINICAL CANCER RESEARCH, 2004, 10 (07) : 2466 - 2472
  • [25] Salt sensitivity of blood pressure in a rat model of polycystic ovary syndrome
    Moulana, Mohadetheh
    Lima, Roberta
    Reckelhoff, Jane F.
    FASEB JOURNAL, 2011, 25
  • [26] Hydroalcoholic extract of flaxseed improves polycystic ovary syndrome in a rat model
    Jelodar, Gholamali
    Masoomi, Sajjad
    Rahmanifar, Farhad
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2018, 21 (06) : 645 - 650
  • [27] Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome
    Zhang, Yuehui
    Hu, Min
    Meng, Fanci
    Sun, Xiaoyan
    Xu, Hongfei
    Zhang, Jiao
    Cui, Peng
    Morina, Njomeza
    Li, Xin
    Li, Wei
    Wu, Xiao-Ke
    Brannstrom, Mats
    Shao, Ruijin
    Billig, Hakan
    EBIOMEDICINE, 2017, 18 : 157 - 170
  • [28] Uterine histopathology and steroid metabolism in a polycystic ovary syndrome rat model
    Bracho, Gisela Soledad
    Acosta, Maria Virginia
    Altamirano, Gabriela Anahi
    Alcaraz, Mirta Raquel
    Montemurro, Milagros
    Culzoni, Maria Julia
    Rossetti, Maria Florencia
    Kass, Laura
    Luque, Enrique Hugo
    Bosquiazzo, Veronica Lis
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2024, 585
  • [29] Hyperandrogenism Decreases Seizure Threshold in a Rat Model of Polycystic Ovary Syndrome
    Zhang, Jiaxian
    Lai, Wanlin
    Tang, Yusha
    Gao, Jing
    Zhou, Xiangyang
    Chen, Lei
    NEUROENDOCRINOLOGY, 2024, 114 (11) : 1005 - 1017
  • [30] Correction to: Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model
    Kai-Lee Wang
    Shih-Min Hsia
    Paulus S. Wang
    Po-Han Lin
    Digestive Diseases and Sciences, 2020, 65 : 3408 - 3409