"Chronic Disseminated Aspergillosis," a Novel Fungal Immune Reconstitution Inflammatory Syndrome

被引：2

作者：

Pourbaix, Annabelle ^{[1
]}

Guery, Romain ^{[1
]}

Bruneau, Julie ^{[2
]}

Blanc, Estelle ^{[3
]}

Jouvion, Gregory ^{[4
,5
]}

Weinandt, Marthe ^{[6
]}

Rouzaud, Claire ^{[1
]}

Lourenco, Jeremy ^{[1
]}

Boutboul, David ^{[7
]}

Mira, Jean-Paul ^{[8
]}

Rouquette, Alexandre ^{[9
]}

Molina, Thierry Jo ^{[2
]}

Lecuit, Marc ^{[1
,10
]}

Lortholary, Olivier ^{[1
,11
]}

机构：

[1] Paris Univ, Necker Enfants Malad Hosp, AP HP, Infect Dis & Trop Med Dept, Paris, France

[2] Paris Descartes Univ, Necker Enfants Malad Hosp, AP HP, Pathol Dept, Paris, France

[3] Marie Lannelongue Hosp, Nucl Med Dept, Le Plessis Robinson, France

[4] Sorbonne Univ, UF Genet Mol, Hop Armand Trousseau, AP HP,Pathophysiol Pediat Genet Dis,INSERM, Paris, France

[5] Inst Pasteur, Expt Neuropathol Unit, Paris, France

[6] Paris Descartes Univ, Cochin Hosp, AP HP, Visceral Surg Dept, Paris, France

[7] Univ Paris, Clin Immunopathol Dept, St Louis Hosp, AP HP,INSERM HIPI U967, Paris, France

[8] Paris Descartes Univ, Cochin Hosp, AP HP, Med Intens Care Dept, Paris, France

[9] Paris Descartes Univ, Cochin Hosp, AP HP, Pathol Dept, Paris, France

[10] Inst Pasteur, Biol Infect Unit, INSERM, U1117, Paris, France

[11] Inst Pasteur, Mol Mycol Unit, CNRS, UMR2000, Paris, France

来源：

OPEN FORUM INFECTIOUS DISEASES | 2020年 / 7卷 / 11期

关键词：

aspergillosis; hepatosplenic; immune reconstitution inflammatory syndrome; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; INVASIVE ASPERGILLOSIS; HEPATIC ASPERGILLOSIS; TRANSPLANTATION; PROGRESSION; THERAPY; DISEASE;

D O I：

10.1093/ofid/ofaa175

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report a case of chronic hepatosplenic aspergillosis following immune reconstitution complicating colic aspergillosis in an AIDS patient with multicentric Castleman disease. Symptoms mimicked the clinical presentation of chronic disseminated candidiasis and responded to corticosteroid. This emerging entity enlarges the spectrum of fungal immune reconstitution inflammatory syndrome in the HIV setting.

引用

页数：4

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