Triterpene Saponins from the Stems of Entada phaseoloides

被引：17
|
作者：
Xiong, Hui [1 ]
Ding, Xin [1 ]
Yang, Xin-zhou [1 ]
Yang, Guang-zhong [1 ]
Mei, Zhi-nan [1 ]
机构：
[1] South Cent Univ Nationalities, Coll Pharm, Wuhan 430074, Peoples R China
来源：
PLANTA MEDICA | 2014年 / 80卷 / 8-9期
基金：
美国国家科学基金会;
关键词：
Entada; Entada phaseoloides; Leguminosae; triterpene saponins; entagenic acid; SULFUR-CONTAINING AMIDE; MEDICINAL-PLANTS; ACID; DERIVATIVES;
D O I：
10.1055/s-0034-1368455
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Ten new triterpene saponins (1-10) have been isolated from the stems of Entada phaseoloides. Their structures were elucidated by spectroscopic analysis and chemical methods. Among these compounds, the aglycons of 6-10 are being reported for the first time, in this study, including 3 beta, 15 alpha, 16 alpha-trihydroxy-11 alpha, 12 alpha-epoxy olean-28,13 beta-olide (6), 3 beta, 15 alpha, 16 alpha-trihydroxy-11-oxo-olean-12-en-28-oic acids (7 and 8), and 3 beta, 15 alpha, 16 alpha-trihydroxy-oleana-11,13(18)-dien-28-oic acids (9 and 10). The cytotoxic activities of all of these compounds were evaluated against HepG-2, A549, and Ec-1 cell lines.
引用
收藏
页码：710 / 718
页数：9
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