Triterpene Saponins from the Stems of Entada phaseoloides

被引：17
|
作者：
Xiong, Hui [1 ]
Ding, Xin [1 ]
Yang, Xin-zhou [1 ]
Yang, Guang-zhong [1 ]
Mei, Zhi-nan [1 ]
机构：
[1] South Cent Univ Nationalities, Coll Pharm, Wuhan 430074, Peoples R China
来源：
PLANTA MEDICA | 2014年 / 80卷 / 8-9期
基金：
美国国家科学基金会;
关键词：
Entada; Entada phaseoloides; Leguminosae; triterpene saponins; entagenic acid; SULFUR-CONTAINING AMIDE; MEDICINAL-PLANTS; ACID; DERIVATIVES;
D O I：
10.1055/s-0034-1368455
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Ten new triterpene saponins (1-10) have been isolated from the stems of Entada phaseoloides. Their structures were elucidated by spectroscopic analysis and chemical methods. Among these compounds, the aglycons of 6-10 are being reported for the first time, in this study, including 3 beta, 15 alpha, 16 alpha-trihydroxy-11 alpha, 12 alpha-epoxy olean-28,13 beta-olide (6), 3 beta, 15 alpha, 16 alpha-trihydroxy-11-oxo-olean-12-en-28-oic acids (7 and 8), and 3 beta, 15 alpha, 16 alpha-trihydroxy-oleana-11,13(18)-dien-28-oic acids (9 and 10). The cytotoxic activities of all of these compounds were evaluated against HepG-2, A549, and Ec-1 cell lines.
引用
收藏
页码：710 / 718
页数：9
相关论文
共 50 条
  • [1] Triterpene Saponins from Entada phaseoloides
    Xiong, Hui
    Mei, Zhinan
    Yang, Guangzhong
    Mo, Shasha
    Yang, Xinzhou
    Zhang, Peng
    Wu, Jizhou
    HELVETICA CHIMICA ACTA, 2013, 96 (08) : 1579 - 1589
  • [2] Triterpene saponins with anti-inflammatory activity from the stems of Entada phaseoloides
    Xiong, Hui
    Zheng, Yanan
    Yang, Guangzhong
    Wang, Huixia
    Mei, Zhinan
    FITOTERAPIA, 2015, 103 : 33 - 45
  • [3] Antioxidant Phenolic Compounds from the Stems of Entada phaseoloides
    Dong, Yuqiong
    Shi, Haiming
    Yang, Haisha
    Peng, Yunhua
    Wang, Mengyue
    Li, Xiaobo
    CHEMISTRY & BIODIVERSITY, 2012, 9 (01) : 68 - 79
  • [4] Two new chalcone glycosides from the stems of Entada phaseoloides
    Zhao, Zhong-xiang
    Jin, Jing
    Lin, Chao-zhan
    Zhu, Chen-chen
    Liu, Yi-ming
    Lin, Ai-hua
    Liu, Ying-xiang
    Zhang, Li
    Luo, Hua-feng
    FITOTERAPIA, 2011, 82 (07) : 1102 - 1105
  • [5] Antiproliferative triterpene saponins from Entada africana
    Cioffi, Giuseppina
    Dal Piaz, Fabrizio
    De Caprariis, Paolo
    Sanogo, Rokia
    Marzocco, Stefania
    Autore, Giuseppina
    De Tommasi, Nunziatina
    JOURNAL OF NATURAL PRODUCTS, 2006, 69 (09): : 1323 - 1329
  • [6] ENTADA SAPONINS ES-II AND ES-IV FROM THE BARK OF ENTADA-PHASEOLOIDES
    OKADA, Y
    SHIBATA, S
    JAVELLANA, AMJ
    KAMO, O
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1988, 36 (04) : 1264 - 1269
  • [7] Pursaethosides A-E, triterpene saponins from Entada pursaetha
    Tapondjou, AL
    Miyamoto, T
    Mirjolet, JF
    Guilbaud, N
    Lacaille-Dubois, MA
    JOURNAL OF NATURAL PRODUCTS, 2005, 68 (08): : 1185 - 1190
  • [8] Entadosides A–D, triterpene saponins and a glucoside of the sulphur-containing amide from the kernel nuts of Entada phaseoloides (L.) Merrill
    Yoshihiro Iwamoto
    Sachiko Sugimoto
    Liva Harinantenaina
    Katsuyoshi Matsunami
    Hideaki Otsuka
    Journal of Natural Medicines, 2012, 66 : 321 - 328
  • [9] Entadosides A-D, triterpene saponins and a glucoside of the sulphur-containing amide from the kernel nuts of Entada phaseoloides (L.) Merrill
    Iwamoto, Yoshihiro
    Sugimoto, Sachiko
    Harinantenaina, Liva
    Matsunami, Katsuyoshi
    Otsuka, Hideaki
    JOURNAL OF NATURAL MEDICINES, 2012, 66 (02) : 321 - 328
  • [10] Triterpenes and triterpene saponins from the stems of Akebia trifoliata
    Mimaki, Y
    Kuroda, M
    Yokosuka, A
    Harada, H
    Fukushima, M
    Sashida, Y
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2003, 51 (08) : 960 - 965
12345