Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan

被引：23

作者：

Hiramatsu, Yukihiro ^{[1
]}

Miyaji, Yusuke ^{[1
,2
]}

Otsuka, Nao ^{[1
]}

Arakawa, Yoshichika ^{[3
]}

Shibayama, Keigo ^{[1
]}

Kamachi, Kazunari ^{[1
]}

机构：

[1] Natl Inst Infect Dis, Tokyo, Japan

[2] St Marianna Univ, Sch Med, Kawasaki, Kanagawa, Japan

[3] Nagoya Univ, Grad Sch Med, Nagoya, Aichi, Japan

来源：

EMERGING INFECTIOUS DISEASES | 2017年 / 23卷 / 04期

关键词：

EUROPEAN COUNTRIES; UNITED-STATES; FITNESS; STRAINS; VACCINE;

D O I：

10.3201/eid2304.161575

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014-2016 (8%) was significantly lower than the frequency in 2005-2007 (41%), 2008-2010 (35%), and 2011-2013 (25%). This reduction was closely associated with changes in genotypes.

引用

页码：699 / 701

页数：3

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