Precancerous Lesions in Cervical Cancer - Statistics

Introduction Cervical cancer is the third most common cancer and the fourth leading cause of cancer-related death among women worldwide, accounting, in 2018, for 9% (530,000) of all malignancies and 8% (275,000) of all cancer deaths. Infection with human papilloma virus (HPV) is known to be the main risk factor for precancerous lesions and cervical cancer, the second most common cancer among women. It demonstrated that the stages of pre-invasive and invasive cells contain oncogenic HPV genomes and epidemiological studies have shown a strong association between HPV and cervical cancer. All stages of pre-invasive and invasive cervical lesions contain oncogenic HPV genomes. Material and methods We have studied the incidence of precancerous lesions in patients aged 25-64 that had Babes Pap smear test within a 3-year period of nationwide screening for cervical cancer screening program. Results and discussions All 3422 patients here hospitalized only one time during this study which started in 2012 and ended in 2016. He has information about the patients age, if they tested positive or negative to ASCUS or LSIL or HSIL, if they were infected with at list one of this virus: Trichomonas, Candida, Coccobacillus, Actinomyces, Herpes simplex virus, Gardnerella and other infections - including HPV. For the statistical analysis we applied a chi(2) test for proportion, in order to see if the patients who were infected with some viruses are most likely to have some lesions or inflammation on the cervix. Conclusion After applying the chi(2) test for proportion we obtained in most of the cases statistical differences alpha = 0.05, p < alpha. So, we can definitely say that an infection can increase the chance of developing cervix lesions or inflammations.