Bone Healing Evaluation in Critical-Size Defects Treated With Xenogenous Bone Plus Porcine Collagen

被引：13
|
作者：
Maciel, Juceleia [1 ]
Correa Momesso, Gustavo Antonio [1 ]
Ramalho-Ferreira, Gabriel [1 ]
Consolaro, Renata Bianco [2 ]
Perri de Carvalho, Paulo Sergio [1 ,2 ]
Faverani, Leonardo Perez [1 ]
Farnezi Bassi, Ana Paula [1 ]
机构：
[1] Univ Estadual Paulista UNESP, Aracatuba Dent Sch, Dept Surg & Integrated Clin, Rua Jose Bonifacio 1193, BR-16015050 Sao Paulo, Brazil
[2] Fac Adamantinenses Integradas, Dept Oral Pathol, Sao Paulo, Brazil
来源：
IMPLANT DENTISTRY | 2017年 / 26卷 / 02期
基金：
巴西圣保罗研究基金会;
关键词：
biomaterials; critical defects; new bone formation; calvaria; histomorphometric; BIO-OSS COLLAGEN; BIO-OSS(R) COLLAGEN; EXTRACTION SOCKETS; REGENERATION; AUGMENTATION; BIOMATERIALS; IMMEDIATE; IMPLANTS; CALVARIA; THERAPY;
D O I：
10.1097/ID.0000000000000572
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Purpose:This study aimed to evaluate the osteoconductive features of Bio-Oss Collagen in large critical-size defects (8 mm).Materials and Methods:Thirty-six adult Wistar Albinus male adult rats were carried out a critical-size defect with a trephine bur of 8 mm in the calvaria. Groups were divided depending on the filling biomaterial as follows: group BO: Bio-Oss (n = 18); group BOC: Bio-Oss Collagen (n = 18). After 7, 30, and 60 days, 6 rats of each group were euthanized with anesthetic overdose. Specimens were laboratory processed for histomorphometric analysis. Histomorphometric data were statistically analyzed by analysis of variance and post-Tukey test (P < 0.05).Results:Statistical differences were found in new bone formation just in the intragroup comparison among periods after 7 and 60 postoperative days, indicating more new bone formation after 60 days (Tukey test, P = 0.029).Conclusion:Under the limitation of this research, it could be concluded that Bio-Oss and Bio-Oss Collagen in this experimental model did not show osteoconductive features.
引用
收藏
页码：296 / 302
页数：7
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