Primary Analysis of Zuma-5: A Phase 2 Study of Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory (R/R) Indolent Non-Hodgkin Lymphoma (iNHL)

被引：87
|
作者：
Jacobson, Caron
Chavez, Julio C.
Sehgal, Alison R.
William, Basem M.
Munoz, Javier
Salles, Gilles
Munshi, Pashna N.
Casulo, Carla
Maloney, David
De Vos, Sven
Reshef, Ran
Leslie, Lori A.
Yakoub-Agha, Ibrahim
Oluwole, Olalekan O.
Fung, Henry C. H.
Rosenblatt, Joseph D.
Rossi, John M.
Goyal, Lovely
Plaks, Vicki
Yang, Yin
Lee, Jennifer
Godfrey, Wayne
Vezan, Remus
Avanzi, Mauro P.
Neelapu, Sattva S.
机构：
来源：
BLOOD | 2020年 / 136卷
关键词：
D O I：
10.1182/blood-2020-136834
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：5
相关论文
共 50 条
  • [21] A Retrospective Intra-Patient Analysis from ZUMA-5: Axicabtagene Ciloleucel (Axi-Cel) Compared with Prior Standard-of-Care Therapy in Patients with Relapsed/Refractory Follicular Lymphoma
    Bachy, Emmanuel
    Neelapu, Sattva S.
    Chavez, Julio C.
    Yakoub-Agha, Ibrahim
    Lui, Christine
    Wulff, Jacob
    Miao, Harry
    Nikolajeva, Olga
    Best, Timothy
    Linot, Camille
    Jacobson, Caron A.
    BLOOD, 2023, 142
  • [22] ZUMA-22: A phase 3, randomized controlled study of axicabtagene ciloleucel (axi-cel) versus standard-of-care therapy in patients with relapsed or refractory (R/R) follicular lymphoma (FL).
    Flinn, Ian W.
    Jacobson, Caron Alyce
    Nastoupil, Loretta J.
    Morschhauser, Franck
    Davies, Andrew
    Buske, Christian
    Corradini, Paolo
    Guillermo, Armando Lopez
    Reshef, Ran
    Parameswaran, Vinod
    Sehgal, Alison
    Tees, Michael Timothy
    Lui, Christine
    Xue, Wei
    Beygi, Sara
    Grechko, Nikolay
    Bolsue, Pisita
    Giovanetti, Alessandro
    To, Christina Ann
    Nahas, Myrna
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [23] Investigating the Influence of Covariates on Axicabtagene Ciloleucel (axi-cel) Kinetics in Patients with Non-Hodgkin's Lymphoma
    Chartier, Magali
    Filosto, Simone
    Peyret, Thomas
    Chiney, Manoj
    Milletti, Francesca
    Budka, Justin
    Ndi, Andre
    Dong, Jinghui
    Vardhanabhuti, Saran
    Mao, Daqin
    Duffull, Stephen
    Dodds, Michael
    Shen, Rhine
    CLINICAL PHARMACOKINETICS, 2024, 63 (09) : 1283 - 1299
  • [24] Earlier Steroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients (Pts) with Relapsed/Refractory Large B Cell Lymphoma (R/R LBCL)
    Topp, Max S.
    van Meerten, Tom
    Hout, Roch
    Minnema, Monique C.
    Milpied, Noel
    Lugtenburg, Pieternella J.
    Thieblemont, Catherine
    Wermke, Martin
    Song, Kevin W.
    Avivi, Irit
    Kuruvilla, John
    Duehrsen, Ulrich
    Chu, Rong
    Zheng, Lianqing
    Plaks, Vicki
    Kerber, Anne
    Kersten, Marie Jose
    MOLECULAR THERAPY, 2020, 28 (04) : 577 - 577
  • [25] Retreatment of Patients With Refractory Large B Cell Lymphoma With Axicabtagene Ciloleucel (Axi-Cel) in ZUMA-1
    Locke, Frederick
    Bartlett, Nancy
    Jacobson, Caron
    Oluwole, Olalekan
    Munoz, Javier
    Lekakis, Lazaros
    Topp, Max
    Avivi, Irit
    Kim, Jenny
    Chu, Rong
    Zheng, Lianqing
    Rossi, John
    Bot, Adrian
    Neelapu, Sattva
    AMERICAN JOURNAL OF HEMATOLOGY, 2020, 95 : S21 - S22
  • [26] Retreatment (reTx) of Patients with Refractory Large B Cell Lymphoma with Axicabtagene Ciloleucel (Axi-Cel) in ZUMA-1
    Locke, Frederick L.
    Bartlett, Nancy L.
    Jacobson, Caron A.
    Oluwole, Olalekan O.
    Munoz, Javier
    Lekakis, Lazaros J.
    Topp, Max S.
    Avivi, Irit
    Kim, Jenny J.
    Chu, Rong
    Zheng, Lianqing
    Rossi, John M.
    Bot, Adrian
    Neelapu, Sattva S.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2020, 20 : S265 - S265
  • [27] Primary Analysis of ZUMA7: A Phase 3 Randomized Trial of Axicabtagene Ciloleucel (Axi-Cel) versus StandardofCare (SOC) Therapy in Patients (Pts) with Relapsed/Refractory (R/R) Large B-Cell Lymphoma (LBCL)
    Ghobadi, Armin
    Locke, Frederick L.
    Miklos, David B.
    Jacobson, Caron A.
    Perales, Miguel-Angel
    Kersten, Marie Jose
    Oluwole, Olalekan O.
    Rapoport, Aaron P.
    McGuirk, Joseph P.
    Pagel, John M.
    Munoz, Javier
    Farooq, Umar
    van Meerten, Tom
    Reagan, Patrick M.
    Sureda, Anna
    Flinn, Ian W.
    Vandenberghe, Peter
    Song, Kevin W.
    Dickinson, Michael
    Minnema, Monique C.
    Riedell, Peter A.
    Leslie, Lori A.
    Chaganti, Sridhar
    Yang, Yin
    Filosto, Simone
    Schupp, Marco
    To, Christina
    Cheng, Paul
    Gordon, Leo I.
    Westin, Jason R.
    MOLECULAR THERAPY, 2022, 30 (04) : 519 - 519
  • [28] A standardized comparison of outcomes in patients (pts) with refractory, aggressive non-hodgkin Lymphoma (rNHL) from the SCHOLAR-1 analysis and the ZUMA-1 study of axicabtagene ciloleucel (axi-cel)
    Neelapu, S. S.
    Locke, F. L.
    Bartlett, N. L.
    Lekakis, L. J.
    Reagan, P. M.
    Miklos, D.
    Jacobson, C. A.
    Braunschweig, I.
    Oluwole, O.
    Siddiqi, T.
    Lin, Y.
    Crump, M.
    Kuruvilla, J.
    Van den Neste, E.
    Link, B. K.
    Farooq, U.
    Navale, L.
    Go, W. Y.
    Wiezorek, J.
    Gisselbrecht, C.
    ANNALS OF ONCOLOGY, 2017, 28
  • [29] Clinical and biologic covariates of outcomes in ZUMA-1: A pivotal trial of axicabtagene ciloleucel (axi-cel; KTE-C19) in patients with refractory aggressive non-Hodgkin lymphoma (r-NHL).
    Locke, Frederick Lundry
    Neelapu, Sattva Swarup
    Bartlett, Nancy L.
    Lekakis, Lazaros J.
    Miklos, David Bernard
    Jacobson, Caron Alyce
    Braunschweig, Ira
    Oluwole, Olalekan
    Siddiqi, Tanya
    Lin, Yi
    Timmerman, John
    Reagan, Patrick Michael
    Bot, Adrian
    Rossi, John
    Navale, Lynn
    Jiang, Yizhou
    Aycock, Jeff
    Elias, Meg
    Wiezorek, Jeffrey S.
    Go, William Y.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [30] Preliminary results of earlier steroid use with axicabtagene ciloleucel (axi-cel) in patients with relapsed/refractory large B-cell lymphoma (R/R LBCL).
    Topp, Max S.
    van Meerten, Tom
    Wermke, Martin
    Lugtenburg, Elly J.
    Minnema, Monique C.
    Song, Kevin W.
    Thieblemont, Catherine
    Jiang, Yizhou
    Plaks, Vicki
    Kerber, Anne
    Kersten, Marie Jose
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
12345