A MULTICOHORT PHASE 1B STUDY (STELLAR-002) OF XL092 IN COMBINATION WITH IMMUNOTHERAPY IN PATIENTS WITH ADVANCED SOLID TUMORS

被引：0
|
作者：
Mcgregor, Bradley [1 ]
Choueiri, Toni [1 ]
Shah, Neil [2 ]
Bajaj, Aung [3 ]
Chahoud, Jad [4 ]
O'Neil, Bert [5 ]
Michalski, Joel [6 ]
Garmezy, Benjamin [7 ]
Jin, Lixian [8 ]
Aziz, Usman [9 ]
Xu, Fiona [9 ]
Motzer, Robert [2 ]
机构：
[1] Dana Farber Canc Inst, Boston, MA USA
[2] Mem Sloan Kettering Canc Ctr, New York, NY USA
[3] Arizona Oncol, Tucson, AZ USA
[4] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[5] Indiana Univ, Indianapolis, IN USA
[6] Nebraska Canc Specialists, Omaha, NE USA
[7] Sarah Cannon Res Inst, Nashville, TN USA
[8] Bristol Myers Squibb, Lawrenceville, NY USA
[9] Exelixis Inc, Alameda, CA USA
来源：
JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2022年 / 10卷
关键词：
D O I：
10.1136/jitc-2022-SITC2022.0742
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
742
引用
收藏
页码：A775 / A775
页数：1
相关论文
共 50 条
  • [21] First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors
    Todd Bauer
    Byong Chul Cho
    Rebecca Heist
    Lyudmila Bazhenova
    Theresa Werner
    Sanjay Goel
    Dong-Wan Kim
    Douglas Adkins
    Richard D. Carvajal
    Ajjai Alva
    Keith Eaton
    Judy Wang
    Yong Liu
    Xiaohong Yan
    Jamie Christensen
    Saskia Neuteboom
    Richard Chao
    Shubham Pant
    Investigational New Drugs, 2022, 40 : 990 - 1000
  • [22] A phase 1b study evaluating the safety and pharmacokinetics (PK) of regorafenib (REG) in combination with cetuximab (CTX) in patients with advanced solid tumors
    Weekes, C.
    Lockhart, A. C.
    Lenz, H-J.
    Lee, J. J.
    Cleton, A.
    Huang, F.
    Sturm, I.
    ANNALS OF ONCOLOGY, 2017, 28
  • [23] A Phase 1b/2 study of galunisertib in combination with nivolumab in solid tumors and NSCLC
    Nadal, Ernest
    Saleh, Mansoor
    Aix, Santiago Ponce
    de Olza, Maria Ochoa
    Patel, Sandip
    Antonia, Scott
    Zhao, Yumin
    Gueorguieva, Ivelina
    Man, Michael
    Estrem, Shawn
    Avsar, Emin
    Lin, Wen Hong
    Benhadji, Karim
    Guba, Susan
    Ales Diaz, Inmaculada
    Nadal, Ernest
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [24] A PHASE 1/1B DOSE ESCALATION AND COHORT EXPANSION STUDY OF MGC018 IN COMBINATION WITH LORIGERLIMAB IN PATIENTS WITH ADVANCED SOLID TUMORS (AST)
    Powderly, John
    Kaminker, Patrick
    Zhao, Enxu
    Casey, Denise
    Shenderov, Eugene
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A789 - A789
  • [25] A PHASE 1/1B DOSE-ESCALATION STUDY OF INTRAVENOUSLY ADMINISTERED SB 11285 ALONE AND IN COMBINATION WITH ATEZOLIZUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS
    Luke, Jason
    Janku, Filip
    Olszanski, Anthony
    Leach, Kevin
    Iyer, Radhakrishnan
    Abbas, Atif
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A224 - A224
  • [26] Phase 1b study of the oral gemcitabine 'Pro-drug' LY2334737 in combination with capecitabine in patients with advanced solid tumors
    Infante, Jeffrey R.
    Benhadji, Karim A.
    Dy, Grace K.
    Fetterly, Gerald
    Ma, Wen Wee
    Bendell, Johanna
    Callies, Sophie
    Adjei, Alex A.
    INVESTIGATIONAL NEW DRUGS, 2015, 33 (02) : 432 - 439
  • [27] Phase 1b dose escalation study of erlotinib in combination with infusional 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced solid tumors
    Hanauske, Axel-R.
    Cassidy, Jim
    Sastre, Javier
    Bolling, Claus
    Jones, Robert J.
    Rakhit, Ashok
    Fettner, Scott
    Brennscheidt, Ulrich
    Feyereislova, Andrea
    Diaz-Rubio, Eduardo
    CLINICAL CANCER RESEARCH, 2007, 13 (02) : 523 - 531
  • [28] A phase 1b study of crenigacestat (LY3039478) in combination with gemcitabine and cisplatin or gemcitabine and carboplatin in patients with advanced or metastatic solid tumors
    Massard, C.
    Cassier, P. A.
    Azaro, A.
    Anderson, B.
    Yuen, E.
    Yu, D.
    Oakley, G., III
    Benhadji, K. A.
    Pant, S.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 90 (04) : 335 - 344
  • [29] Phase 1b study to assess the safety, tolerability, and clinical activity of pamiparib in combination with temozolomide in patients with locally advanced or metastatic solid tumors
    Stradella, Agostina
    Johnson, Melissa
    Goel, Sanjay
    Park, Haeseong
    Lakhani, Nehal
    Arkenau, Hendrik-Tobias
    Galsky, Matthew D.
    Calvo, Emiliano
    Baz, Vicente
    Moreno, Victor
    Saavedra, Omar
    Luen, Stephen J.
    Mu, Song
    Wan, Qiting
    Chang, Victoria
    Zhang, Wa
    Barve, Minal
    CANCER MEDICINE, 2024, 13 (13):
  • [30] A phase 1b study of crenigacestat (LY3039478) in combination with gemcitabine and cisplatin or gemcitabine and carboplatin in patients with advanced or metastatic solid tumors
    C. Massard
    P. A. Cassier
    A. Azaro
    B. Anderson
    E. Yuen
    D. Yu
    G. Oakley
    K. A. Benhadji
    S. Pant
    Cancer Chemotherapy and Pharmacology, 2022, 90 : 335 - 344
12345