The third mission of universities: the entrepreneurial university

Goal: This article aims to analyze the productions in scientific journals of international bases, in English, Portuguese or Spanish, about entrepreneurial university and third mission, focusing on the productions of Brazilian authors, through a systematic search of the literature. Design / Methodology / Approach: We use the SSF - Systematic Search Flow method, which is applied in systematic and integrative reviews. Results: An entrepreneurial university, committed to the development of its region, is the key factor in achieving regional innovation, a key institution in knowledge-based societies. In the age of knowledge, the university is as important as industry and government; fundamental for the development of knowledge and innovation. As a result, we identified research challenges and opportunities, contributing to the construction of a panorama of Brazilian scientific production in international journals on the themes entrepreneurial university and third mission. Limitations of the investigation: The most important limitation in this study was the long-time collection of research data. Practical implications: Universities must strengthen their relationship with industry and government to transfer knowledge and, at the same time, demonstrate their contribution to the community, fulfilling their third mission, as a vector for regional socioeconomic growth. Originality / Value: We see the opportunity to consolidate studies on the relationship between the third mission and the entrepreneurial university appropriate to the Brazilian reality.