CANCER Mutant p53 and chromatin regulation

被引：21
|
作者：
Prives, Carol [1 ]
Lowe, Scott W. [2 ]
机构：
[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA
[2] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA
来源：
NATURE | 2015年 / 525卷 / 7568期
关键词：
MUTATIONS;
D O I：
10.1038/nature15212
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The finding that genes encoding enzymes that modify histone proteins are among the targets of certain mutant forms of the p53 protein sheds light on how these mutations cause cancer beyond p53 inactivation. See Article p.206
引用
收藏
页码：199 / 200
页数：3
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