The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective

被引：922

作者：

Mahmood, Syed S. ^{[1
]}

Levy, Daniel ^{[2
,3
]}

Vasan, Ramachandran S. ^{[2
,4
,5
]}

Wang, Thomas J. ^{[2
,6
]}

机构：

[1] Harvard Univ, Sch Med, Dept Med, Massachusetts Gen Hosp, Boston, MA USA

[2] NHLBI, Framingham Heart Study, Framingham, MA USA

[3] NHLBI, Populat Res Branch, Div Intramural Res, NIH, Bethesda, MD 20892 USA

[4] Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA

[5] Boston Univ, Sch Med, Whitaker Cardiovasc Inst, Boston, MA 02118 USA

[6] Vanderbilt Univ, Div Cardiovasc Med, Nashville, TN 37235 USA

来源：

LANCET | 2014年 / 383卷 / 9921期

关键词：

RISK-FACTORS; FOLLOW-UP; SYSTOLIC HYPERTENSION; ATRIAL-FIBRILLATION; DIABETES-MELLITUS; NATURAL-HISTORY; BLOOD-PRESSURE; FAILURE; POPULATION; MORTALITY;

D O I：

10.1016/S0140-6736(13)61752-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

On Sept 29, 2013, the Framingham Heart Study will celebrate 65 years since the examination of the first volunteer in 1948. During this period, the study has provided substantial insight into the epidemiology and risk factors of cardiovascular disease. The origins of the study are closely linked to the cardiovascular health of President Franklin D Roosevelt and his premature death from hypertensive heart disease and stroke in 1945. In this Review we describe the events leading to the foundation of the Framingham Heart Study, and provide a brief historical overview of selected contributions from the study.

引用

页码：999 / 1008

页数：10

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